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| Clinical data | |
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| Other names | 4-Propionyloxy-MET; 4-Propionyloxy-N-methyl-N-ethyltryptamine; O-Propionyl-4-HO-MET; O-Propionylmetocin |
| Routes of administration | Oral [1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
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| Identifiers | |
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| PubChem CID | |
| Chemical and physical data | |
| Formula | C16H22N2O2 |
| Molar mass | 274.364 g·mol−1 |
| 3D model (JSmol) | |
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4-PrO-MET, also known as 4-propionyloxy-N-methyl-N-ethyltryptamine or as O-propionyl-4-HO-MET, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to 4-AcO-DMT (psilacetin). [1] It is thought to be a prodrug of 4-HO-MET (metocin) similarly to 4-AcO-MET (metacetin). [1] 4-PrO-MET was encountered online as a novel designer drug in August or September 2025. [1] It is anecdotally claimed to produce more intense psychedelic visuals than psilocin (4-HO-DMT) but to be "less heavy" and to have good tolerability. [1]
| Tryptamines |
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|---|---|
| 4-Hydroxytryptamines and esters/ethers |
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| 5-Hydroxy- and 5-methoxytryptamines |
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| N-Acetyltryptamines |
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| α-Alkyltryptamines |
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| α-Ketotryptamines | |
| Cyclized tryptamines |
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| Isotryptamines | |
| Related compounds |
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