4-AcO-DET

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4-AcO-DET
4-AcO-DET.svg
4-Acetoxy-N,N-diethyltryptamine.png
Clinical data
Other names4-Acetoxy-DET; 4-Acetoxy-N,N-diethyltryptamine; Ethacetin; Ethylacybin
Routes of
administration 		Oral [1]
Drug class Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
Pharmacokinetic data
Duration of action 4–6 hours [1]
Identifiers
  • 3-(2-diethylaminoethyl)-1H-indol-4-yl acetate
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C16H22N2O2
Molar mass 274.364 g·mol−1
3D model (JSmol)
  • CC(OC1=CC=CC2=C1C(CCN(CC)CC)=CN2)=O
  • InChI=1S/C16H22N2O2/c1-4-18(5-2)10-9-13-11-17-14-7-6-8-15(16(13)14)20-12(3)19/h6-8,11,17H,4-5,9-10H2,1-3H3 Yes check.svgY
  • Key:ODVLAYUXIAMBFN-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

4-AcO-DET, also known as 4-acetoxy-N,N-diethyltryptamine as well as ethacetin or ethylacybin, is a psychedelic tryptamine. [1] It was first synthesized in 1958 by Albert Hofmann in the Sandoz lab. [2]

Contents

Use and effects

4-AcO-DET is orally active, and doses of 10 to 25 mg are common. [1] Effects last 4 to 6 hours. [1] The free base is also active when smoked in a dose range of 5 to 20 mg. [2] Smoking 4-AcO-DET greatly speeds up the onset; peak effects are experienced within 10 minutes, and are usually over within 1 hour.[ specify ]

Interactions

Pharmacology

It is expected that 4-AcO-DET is quickly hydrolyzed into the free phenolic 4-HO-DET by serum esterases, but human studies concerning the metabolic fate of this drug are lacking. [1]

Society and culture

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-AcO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-acetoxi-N,N-dietyltryptamin (4-AcO-DET), making it illegal to sell or possess. [3]

See also

References

  1. 1 2 3 4 5 6 Shulgin A, Shulgin A. "#16. 4-HO-DET". Tikhal: The Chemistry Continues. Retrieved 19 April 2007.
  2. 1 2 Erowid 4-Acetoxy-DET Vaults : Primer. Accessed on April 19, 2007.
  3. ↑ Svensk författningssamling (13 October 2005). "Förordning om ändring i förordningen (1999:58) om förbud mot vissa hälsofarliga varor;" (PDF). Archived from the original (PDF) on 4 March 2016. Retrieved October 10, 2015.
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