Plakophilin

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Plakophilin are proteins of the cytoskeleton. [1] They are involved in regulating the adhesive activity of cadherin. [2]

The three types of plakophilin proteins found in humans are PKP1, PKP2, and PKP3; all exhibiting dual localization in the nucleus as well as desmosomes. [3] [4]

Genes include:

See also

References

  1. ↑ Plakophilins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  2. ↑ Kline CF, Mohler PJ (2013-01-01). Bennett V (ed.). "Evolving form to fit function: cardiomyocyte intercalated disc and transverse-tubule membranes" . Current Topics in Membranes. Functional Organization of Vertebrate Plasma Membrane. 72. Academic Press: 121–58. doi:10.1016/b978-0-12-417027-8.00004-0. PMID   24210429 . Retrieved 2020-10-22.
  3. ↑ Schwab M, ed. (2011). Encyclopedia of Cancer (2011 ed.). Springer, Berlin, Heidelberg. p. 252. doi:10.1007/978-3-642-16483-5. ISBN   978-3-642-16483-5. S2CID   27502611.
  4. ↑ Miller RK, Hong JY, Muñoz WA, McCrea PD (January 2013). van Roy F (ed.). "Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling". Progress in Molecular Biology and Translational Science. The Molecular Biology of Cadherins. 116. Academic Press: 387–407. doi:10.1016/b978-0-12-394311-8.00017-0. PMC   3752792 . PMID   23481204.
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