TUBA1B

Last updated
TUBA1B
Protein TUBA1B PDB 1ffx.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TUBA1B , K-ALPHA-1, tubulin alpha 1b
External IDs OMIM: 602530; MGI: 107804; HomoloGene: 134527; GeneCards: TUBA1B; OMA:TUBA1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006082

NM_011654

RefSeq (protein)

NP_006073

NP_035784

Location (UCSC) Chr 12: 49.13 – 49.13 Mb Chr 15: 98.83 – 98.83 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tubulin alpha-1B chain is a protein that in humans is encoded by the TUBA1B gene. [5] [6] [7]


Interactions

TUBA1B has been shown to interact with PIK3R1. [8] Antibodies against tubulin alpha 1b can be used as markers for microtubules and spindles. [9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000123416 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000023004 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Banerjee A (Jun 2002). "Increased levels of tyrosinated alpha-, beta(III)-, and beta(IV)-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells". Biochem Biophys Res Commun. 293 (1): 598–601. doi:10.1016/S0006-291X(02)00269-3. PMID   12054644.
  6. Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW (Jan 1984). "Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions". Mol Cell Biol. 3 (10): 1738–45. doi:10.1128/mcb.3.10.1738. PMC   370035 . PMID   6646120.
  7. "Entrez Gene: TUBA1B tubulin, alpha 1b".
  8. Kapeller, R; Toker A; Cantley L C; Carpenter C L (Oct 1995). "Phosphoinositide 3-kinase binds constitutively to alpha/beta-tubulin and binds to gamma-tubulin in response to insulin". J. Biol. Chem. 270 (43). UNITED STATES: 25985–91. doi: 10.1074/jbc.270.43.25985 . ISSN   0021-9258. PMID   7592789.
  9. "Anti-alpha Tubulin antibody [GT114] (GTX628802) | GeneTex".

Further reading