KRT27

KRT27
Identifiers
Aliases	KRT27 , KRT25C, K25IRS3, keratin 27
External IDs	OMIM: 616676; MGI: 1339999; HomoloGene: 7805; GeneCards: KRT27; OMA:KRT27 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	40,782,550 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	99,241,930 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; testicle; ; skin of hip; ; skin of leg; ; skin of abdomen; ; nipple; ; right lung; ; right coronary artery; ; mucosa of transverse colon; ; gallbladder;
	Top expressed in
	hair follicle; ; lip; ; lumbar spinal ganglion; ; skin of back; ; skin of abdomen; ; embryo; ; lower jaw; ; Meckel's cartilage; ; skin of external ear; ; sexually immature organism;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural molecule activity ; molecular function ;
Cellular component	cytoplasm ; extracellular exosome ; intermediate filament ; cytosol ;
Biological process	hair follicle morphogenesis ; keratinization ; cornification ; biological process ;
	Sources:Amigo / QuickGO
Orthologs
	342574
	16675
	ENSG00000171446
	ENSMUSG00000017588
	Q7Z3Y8
	Q9Z320
	NM_181537
	NM_010666
	NP_853515
	NP_034796
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 15, 2024

Keratin, type I cytoskeletal 27 is a keratin belonging to the Type I family of intermediate filament proteins.^[5] In humans, in it encoded by a gene with symbol KRT27.

Related Research Articles

Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined. Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins. In humans Keratin 6A is encoded by the KRT6A gene.

RAI1 is a transcription factor associated with Smith–Magenis syndrome when individuals have deletions of the gene and Potocki–Lupski syndrome when individuals have a duplication. It is known as retinoic acid induced 1.

Olfactory receptor 51B6 is a protein that in humans is encoded by the OR51B6 gene.

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.

Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.

Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene.

Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.

Collagen, type XXVIII, alpha 1 also known as COL28A1 is a protein that in humans is encoded by the COL28A1 gene. This protein belongs to a class of collagens that contain von Willebrand factor type A domains. The protein is encoded by the COL28A1 gene which contains 45 exons and is found of the p arm of chromosome 7.

Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.

Keratin 80, also known as KRT80, is a protein which humans is encoded by the KRT80 gene.

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.

KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.

KRT40 is a keratin gene that encodes for keratin40, a type I keratin expressed in the kidney.

KRT39 is a keratin gene. The encoded protein is a type I keratin.

KRT28 is a keratin gene.

KRT25 is a gene encoding for a protein in the type I keratin family. The gene is encoded on a region of chromosome 17q21.2.

Keratin, type I cuticular Ha5 is a keratin protein that in humans is encoded by the KRT35 gene. The protein is a type I keratin and a hair keratin.

Dynein axonemal light chain 1, (LC1) is a protein that in humans is encoded by the DNAL1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000171446 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000017588 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "KRT27 keratin 27 - NIH Genetic Testing Registry (GTR) - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-06-25.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000171446 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000017588 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] "KRT27 keratin 27 - NIH Genetic Testing Registry (GTR) - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2023-06-25.

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