MYO1B

MYO1B
Identifiers
Aliases	MYO1B , myr1, myosin IB, MMIa, MMI-alpha, MYH-1c
External IDs	OMIM: 606537; MGI: 107752; HomoloGene: 7856; GeneCards: MYO1B; OMA:MYO1B - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q32.3 Start 191,245,185 bp [1] End 191,425,389 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 C1.1|1 26.58 cM Start 51,788,924 bp [2] End 51,955,230 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in visceral pleura liver right lobe of liver islet of Langerhans lower lobe of lung right lung hair follicle stromal cell of endometrium tibia parietal pleura Top expressed in genital tubercle tail of embryo lumbar spinal ganglion right lung lens right lung lobe seminal vesicula left lung left lobe of liver calvaria More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding calmodulin binding microfilament motor activity actin binding phosphatidylinositol-4,5-bisphosphate binding cytoskeletal motor activity ATP binding phosphatidylinositol-3,4,5-trisphosphate binding actin filament binding cadherin binding Cellular component cytoplasm trans-Golgi network membrane filopodium early endosome brush border actin filament perinuclear region of cytoplasm endosome membrane extracellular exosome cell periphery myosin complex plasma membrane apical part of cell Biological process actin filament organization actin filament-based movement actin filament bundle assembly post-Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4430 17912 Ensembl ENSG00000128641 ENSMUSG00000018417 UniProt O43795 P46735 RefSeq (mRNA) NM_001130158 NM_001161819 NM_012223 NM_001330237 NM_001330238 NM_001161817 NM_001290982 NM_010863 RefSeq (protein) NP_001123630 NP_001155291 NP_001317166 NP_001317167 NP_036355 NP_001155289 NP_001277911 NP_034993 Location (UCSC) Chr 2: 191.25 – 191.43 Mb Chr 1: 51.79 – 51.96 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000128641 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018417 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bement WM, Hasson T, Wirth JA, et al. (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. Bibcode:1994PNAS...91.6549B. doi: 10.1073/pnas.91.14.6549 . PMC   44240 . PMID   8022818.
6. Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC   2119751 . PMID   8449985.
7. "Entrez Gene: MYO1B myosin IB".

Further reading

• Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell Sci. 108 (12): 3775–86. doi:10.1242/jcs.108.12.3775. PMID   8719884.
• Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. Bibcode:2001CBio...11.1131T. doi: 10.1016/S0960-9822(01)00320-7 . PMID   11509238. S2CID   2678512.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC   3202438 . PMID   12486594.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID   16219689. S2CID   14698224.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.