KRT32

Last updated

KRT32
Identifiers
Aliases KRT32 , HA2, HKA2, KRTHA2, hHa2, keratin 32
External IDs OMIM: 602760; MGI: 1309995; HomoloGene: 68246; GeneCards: KRT32; OMA:KRT32 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002278

NM_001159374
NM_010665

RefSeq (protein)

NP_002269

NP_001152846

Location (UCSC) Chr 17: 41.46 – 41.47 Mb Chr 11: 99.97 – 99.98 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene. [5] [6] [7] [8]

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription. [8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000108759 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046095 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Rogers MA, Nischt R, Korge B, Krieg T, Fink TM, Lichter P, Winter H, Schweizer J (Nov 1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes". Exp Cell Res. 220 (2): 357–62. doi:10.1006/excr.1995.1326. PMID   7556444.
  6. Rogers MA, Winter H, Langbein L, Krieg T, Schweizer J (Dec 1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5". J Invest Dermatol. 107 (4): 633–8. doi: 10.1111/1523-1747.ep12584243 . PMID   8823373.
  7. Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC   2064177 . PMID   16831889.
  8. 1 2 "Entrez Gene: KRT32 keratin 32".

Further reading