KRT80

KRT80
Identifiers
Aliases	KRT80 , KB20, keratin 80
External IDs	OMIM: 611161; MGI: 1921377; HomoloGene: 66610; GeneCards: KRT80; OMA:KRT80 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	52,192,014 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	101,268,043 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of arm; ; skin of leg; ; skin of thigh; ; amniotic fluid; ; skin of hip; ; gums; ; gingival epithelium; ; vulva; ; human penis;
	Top expressed in
	lip; ; esophagus; ; skin of external ear; ; skin of back; ; right lung; ; granulocyte; ; right lung lobe; ; molar; ; external naris; ; conjunctival fornix;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; structural molecule activity ;
Cellular component	cytoplasm ; desmosome ; keratin filament ; intermediate filament ; cytosol ; intermediate filament cytoskeleton ;
Biological process	keratinization ; cornification ;
	Sources:Amigo / QuickGO
Orthologs
	144501
	74127
	ENSG00000167767
	ENSMUSG00000037185
	Q6KB66
	Q0VBK2
	NM_001081492 ; NM_182507
	NM_028770
	NP_001074961 ; NP_872313
	NP_083046
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 01, 2024

Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.^[5]^[6]

Function

Keratins, such as KRT80, are filament proteins that make up one of the major structural fibers of epithelial cells.^[7]

Related Research Articles

Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined. Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins. In humans Keratin 6A is encoded by the KRT6A gene.

Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene.

Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II cytokeratin. It is specifically found in the corneal epithelium together with keratin 12.

Keratin 12 is a protein that in humans is encoded by the KRT12 gene. It's a type I keratin.

Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene. Keratin 10 is a type I keratin.

Keratin 9 is a protein that in humans is encoded by the KRT9 gene.

Keratin, type II cuticular Hb1 is a protein that in humans is encoded by the KRT81 gene.

Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene.

Keratin, type II cuticular Hb6 is a protein that in humans is encoded by the KRT86 gene.

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.

Keratin, type I cuticular Ha3-I is a protein that in humans is encoded by the KRT33A gene.

Keratin, type I cuticular Ha4 is a protein that in humans is encoded by the KRT34 gene.

Keratin, type II cuticular Hb5 is a protein that in humans is encoded by the KRT85 gene.

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.

Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.

KRT71 is a keratin gene. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000167767 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037185 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177 . PMID 16831889.
↑ "Entrez Gene: KRT80 keratin 80".
↑ Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J (March 2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi: 10.1111/j.0022-202X.2004.23530.x . PMID 15737194.

KRT80

Contents

Function

Related Research Articles

References

Further reading