KRT38

KRT38
Identifiers
Aliases	KRT38 , HA8, KRTHA8, hHa8, keratin 38
External IDs	OMIM: 604542; HomoloGene: 68361; GeneCards: KRT38; OMA:KRT38 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,440,983 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; skin of thigh; ; skin of abdomen; ; pharynx; ; tonsil; ; head; ; gonad; ; mouth; ; mucosa of esophagus; ; salivary gland;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; structural molecule activity ;
Cellular component	intermediate filament ; extracellular exosome ; cytosol ;
Biological process	keratinization ; cornification ;
	Sources:Amigo / QuickGO
Orthologs
	8687
	n/a
	ENSG00000171360
	n/a
	O76015
	n/a
	NM_006771
	n/a
	NP_006762
	n/a
	Wikidata
View/Edit Human

Last updated September 20, 2025

KRT38 is a keratin gene. Its corresponding protein is asymmetrically distributed within human hair follicles.^[3] It does not have murine^[4] or equine^[5] orthologs. The encoded protein is a type I keratin and a hair keratin.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000171360 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Westgate GE, Ginger RS, Green MR (June 2017). "The biology and genetics of curly hair". Experimental Dermatology. 26 (6): 483–490. doi: 10.1111/exd.13347 . hdl: 10454/14702 . PMID 28370528. S2CID 44671559.
↑ Takan I, Karakülah G, Louka A, Pavlopoulou A (17 March 2023). ""In the light of evolution:" keratins as exceptional tumor biomarkers". PeerJ. 11 e15099. doi: 10.7717/peerj.15099 . PMC 10026720 . PMID 36949761.
↑ Balmer P, Bauer A, Pujar S, McGarvey KM, Welle M, Galichet A, et al. (28 August 2017). "A curated catalog of canine and equine keratin genes". PLOS ONE. 12 (8) e0180359. Bibcode:2017PLoSO..1280359B. doi: 10.1371/journal.pone.0180359 . PMC 5573215 . PMID 28846680.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000171360 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] Westgate GE, Ginger RS, Green MR (June 2017). "The biology and genetics of curly hair". Experimental Dermatology. 26 (6): 483–490. doi: 10.1111/exd.13347 . hdl: 10454/14702 . PMID 28370528. S2CID 44671559.

[4] Takan I, Karakülah G, Louka A, Pavlopoulou A (17 March 2023). ""In the light of evolution:" keratins as exceptional tumor biomarkers". PeerJ. 11 e15099. doi: 10.7717/peerj.15099 . PMC 10026720 . PMID 36949761.

[5] Balmer P, Bauer A, Pujar S, McGarvey KM, Welle M, Galichet A, et al. (28 August 2017). "A curated catalog of canine and equine keratin genes". PLOS ONE. 12 (8) e0180359. Bibcode:2017PLoSO..1280359B. doi: 10.1371/journal.pone.0180359 . PMC 5573215 . PMID 28846680.

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