Tubulin beta chain is a protein that in humans is encoded by the TUBB gene. [5] [6] [7]
Tubulin beta chain is a protein that in humans is encoded by the TUBB gene. [5] [6] [7]
TUBB has been shown to interact with NCOA6 [8] and SYT9. [9]
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division.
Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene.
Class III β-tubulin, otherwise known as βIII-tubulin (β3-tubulin) or β-tubulin III, is a microtubule element of the tubulin family found almost exclusively in neurons, and in testis cells. In humans, it is encoded by the TUBB3 gene.
Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene.
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIα), a.k.a.Ca2+/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene.
Microtubule-associated protein 2 is a protein in humans that is encoded by the MAP2 gene.
Heat shock protein HSP 90-beta also called HSP90beta is a protein that in humans is encoded by the HSP90AB1 gene.
Microtubule-associated protein 4 is a protein that in humans is encoded by the MAP4 gene.
Tubulin beta-2A chain is a protein that in humans is encoded by the TUBB2A gene.
Guanine nucleotide-binding protein G(i), alpha-1 subunit is a protein that in humans is encoded by the GNAI1 gene.
Tubulin alpha-4A chain is a protein that in humans is encoded by the TUBA4A gene.
Tubulin alpha-1A chain is a protein that in humans is encoded by the TUBA1A gene.
Tubulin alpha-1B chain is a protein that in humans is encoded by the TUBA1B gene.
Tubulin alpha-3C/D chain is a protein that in humans is encoded by the TUBA3C gene.
Tubulin beta-4B chain formerly known as tubulin beta-2C chain is a protein that in humans is encoded by the TUBB4B gene.
Lysine-specific demethylase 5A is an enzyme that in humans is encoded by the KDM5A gene.
Tubulin beta-4A chain is a protein that in humans is encoded by the TUBB4A gene. Two tubulin beta-4 chain proteins are encoded in the human genome by the genes TUBB4A and TUBB4B. Tubulin is the major constituent of microtubules, a key components of the cytoskeleton. It binds two molecules of GTP, one at an exchangeable site on the beta-chain and one at a non-exchangeable site on the alpha-chain. TUBB4A is preferentially and highly expressed in the central nervous system.
Pericentrin (kendrin), also known as PCNT and pericentrin-B (PCNTB), is a protein which in humans is encoded by the PCNT gene on chromosome 21. This protein localizes to the centrosome and recruits proteins to the pericentriolar matrix (PCM) to ensure proper centrosome and mitotic spindle formation, and thus, uninterrupted cell cycle progression. This gene is implicated in many diseases and disorders, including congenital disorders such as microcephalic osteodysplastic primordial dwarfism type II (MOPDII) and Seckel syndrome.
Katanin p80 WD40-containing subunit B1 is a protein that in humans is encoded by the KATNB1 gene.
2′,3′-Cyclic-nucleotide 3'-phosphodiesterase is an enzyme that in humans is encoded by the CNP gene.
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