CLCA4

Last updated
CLCA4
Identifiers
Aliases CLCA4 , CaCC, CaCC2, chloride channel accessory 4
External IDs OMIM: 616857 MGI: 2139744 HomoloGene: 40808 GeneCards: CLCA4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012128

NM_207208

RefSeq (protein)

NP_036260

NP_997091

Location (UCSC) Chr 1: 86.55 – 86.58 Mb Chr 3: 144.95 – 144.98 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Chloride channel accessory 4, also known as CLCA4, is a protein which in humans CLCA4 gene. The protein encoded by this gene is a chloride channel. [5] Protein structure prediction methods suggest the N-terminal region of CLCA4 protein is a zinc metalloprotease, and the protein is not an ion channel per se. [6]

Contents

See also

Related Research Articles

CLCA1

Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.

CLIC4

Chloride intracellular channel 4, also known as CLIC4, is a eukaryotic gene.

CACNB4

Voltage-dependent L-type calcium channel subunit beta-4 is a protein that in humans is encoded by the CACNB4 gene.

CLCA2

Chloride channel accessory 2 is a protein that in humans is encoded by the CLCA2 gene.

KCNMB2

Calcium-activated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNMB2 gene.

CLCN6

Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.

PCSK4

Proprotein convertase subtilisin/kexin type 4 is an enzyme that in humans is encoded by the PCSK4 gene.

Choline transporter-like protein 4

Choline transporter-like protein 4 is a protein that in humans is encoded by the SLC44A4 gene.

Allograft inflammatory factor 1-like

Allograft inflammatory factor 1-like is a protein that is encoded by the AIF1L gene in humans.

Mucin 20

Mucin-20 is a protein that in humans is encoded by the MUC20 gene.

LRP10

Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the LRP10 gene.

KCNMB4

Calcium-activated potassium channel subunit beta-4 is a protein that in humans is encoded by the KCNMB4 gene.

ATRAID

Apoptosis-related protein 3 is a protein that in humans is encoded by the ATRAID gene.

KIRREL2

Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the KIRREL2 gene. It is primarily expressed in β cells of the pancreatic islets.

KCNK17

Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene.

TOX4

TOX4 also known as KIAA0737, is a human gene.

KCNAB3

Voltage-gated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNAB3 gene. The protein encoded by this gene is a voltage-gated potassium channel beta subunit.

CLCA3

Chloride channel accessory 3, also known as CLCA3, is a protein which in humans is encoded by the CLCA3P pseudogene. The protein encoded by this gene is a chloride channel. According to the HGNC, this protein is not expressed in humans but is in certain other species such as mouse. However, some conflicting reports state that human cells produce and glycosylate this protein.

CLIC3

Chloride intracellular channel protein 3 is a protein that in humans is encoded by the CLIC3 gene. This protein is a chloride channel.

Dipeptidase 3

Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000016602 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068547 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Agnel M, Vermat T, Culouscou JM (July 1999). "Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea". FEBS Lett. 455 (3): 295–301. doi:10.1016/S0014-5793(99)00891-1. PMID   10437792. S2CID   82094058.
  6. Pawłowski K, Lepistö M, Meinander N, et al. (2006). "Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels". Proteins. 63 (3): 424–39. doi:10.1002/prot.20887. PMID   16470849. S2CID   40041491.

Further reading