KCNT2

KCNT2
Identifiers
Aliases	KCNT2 , KCa4.2, SLICK, SLO2.1, potassium sodium-activated channel subfamily T member 2, EIEE57, DEE57
External IDs	OMIM: 610044 MGI: 3036273 HomoloGene: 16121 GeneCards: KCNT2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	196,609,225 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	140,539,805 bp
RNA expression pattern
	Top expressed in
	parietal pleura; ; endothelial cell; ; Brodmann area 23; ; Brodmann area 46; ; middle temporal gyrus; ; germinal epithelium; ; Achilles tendon; ; visceral pleura; ; right coronary artery; ; left coronary artery;
	Top expressed in
	aortic valve; ; prefrontal cortex; ; vas deferens; ; primary motor cortex; ; ascending aorta; ; medial dorsal nucleus; ; cingulate gyrus; ; dentate gyrus; ; Region I of hippocampus proper; ; hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity ; ATP binding ; nucleotide binding ; potassium channel activity ; calcium-activated potassium channel activity ; intracellular sodium activated potassium channel activity ; outward rectifier potassium channel activity ; chloride-activated potassium channel activity ;
Cellular component	voltage-gated potassium channel complex ; integral component of membrane ; plasma membrane ; membrane ;
Biological process	potassium ion transmembrane transport ; potassium ion transport ; ion transport ; regulation of membrane potential ; potassium ion export across plasma membrane ;
	Sources:Amigo / QuickGO
Orthologs
	343450
	240776
	ENSG00000162687
	ENSMUSG00000052726
	Q6UVM3
	n/a
	NM_001287819 ; NM_001287820 ; NM_198503
	NM_001081027
	NP_001274748 ; NP_001274749 ; NP_940905
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Potassium channel subfamily T, member 2, also known as KCNT2 is a human gene that encodes the K_Na protein. KCNT2, also known as the Slick channel (sequence like an intermediate calcium channel) is an outwardly rectifying potassium channel activated by internal raises in sodium or chloride ions.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000162687 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052726 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

KCNT2

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References

Further reading