KCNIP1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | KCNIP1 , KCHIP1, VABP, potassium voltage-gated channel interacting protein 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604660; MGI: 1917607; HomoloGene: 22824; GeneCards: KCNIP1; OMA:KCNIP1 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Kv channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene. [5] [6]
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs, also frequently called "KChIP"), which belong to the recoverin branch of the EF-hand superfamily. [7] Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms. [6]
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: CS1 maint: multiple names: authors list (link)This article incorporates text from the United States National Library of Medicine, which is in the public domain.