TRPC7

TRPC7
Identifiers
Aliases	TRPC7 , TRP7, transient receptor potential cation channel subfamily C member 7
External IDs	MGI: 1349470; HomoloGene: 22689; GeneCards: TRPC7; OMA:TRPC7 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q31.1 Start 136,212,745 bp [1] End 136,365,545 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 B1 Start 56,920,926 bp [2] End 57,043,806 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell testicle secondary oocyte gonad human kidney rectum duodenum right testis anterior pituitary Hypothalamus Top expressed in lateral septal nucleus anterior amygdaloid area ventromedial nucleus intestinal villus paraventricular nucleus of hypothalamus globus pallidus deep cerebellar nuclei olfactory tubercle lateral hypothalamus medial dorsal nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function store-operated calcium channel activity ion channel activity protein binding calcium channel activity inositol 1,4,5 trisphosphate binding Cellular component integral component of membrane nuclear envelope membrane cis-Golgi network plasma membrane integral component of plasma membrane perinuclear region of cytoplasm nucleus cation channel complex Biological process regulation of cytosolic calcium ion concentration ion transport single fertilization platelet activation calcium ion transmembrane transport manganese ion transport calcium ion transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57113 26946 Ensembl ENSG00000069018 ENSMUSG00000021541 UniProt Q9HCX4 Q9WVC5 RefSeq (mRNA) NM_001167576 NM_001167577 NM_020389 NM_001376901 NM_012035 NM_001302372 NM_001302373 RefSeq (protein) NP_001161048 NP_001161049 NP_065122 NP_001363830 NP_001289301 NP_001289302 NP_036165 Location (UCSC) Chr 5: 136.21 – 136.37 Mb Chr 13: 56.92 – 57.04 Mb PubMed search [3] [4]
Wikidata
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Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name.

See also

• TRPC

References

1. GRCh38: Ensembl release 89: ENSG00000069018 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021541 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

Further reading

• Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. Vol. 704. Berlin: Springer. p. 700. ISBN   978-94-007-0264-6.
• Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID   16382100. S2CID   17936350.
• Numaga T, Wakamori M, Mori Y (2007). "TRPC7". Transient Receptor Potential (TRP) Channels. Handbook of Experimental Pharmacology. Vol. 179. pp. 143–51. doi: 10.1007/978-3-540-34891-7_8 . ISBN   978-3-540-34889-4. PMID   17217055.

External links

• TRPC7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.