KCNG2

KCNG2
Identifiers
Aliases	KCNG2 , KCNF2, KV6.2, potassium voltage-gated channel modifier subfamily G member 2
External IDs	OMIM: 605696 MGI: 3694646 HomoloGene: 8178 GeneCards: KCNG2
Gene location (Human)
Chr.	Chromosome 18 (human)
End	79,900,184 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	80,407,469 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; secondary oocyte; ; nucleus accumbens; ; hippocampus proper; ; Brodmann area 9; ; amygdala; ; gastrocnemius muscle; ; blood; ; monocyte; ; putamen;
	Top expressed in
	interventricular septum; ; myocardium of ventricle; ; superior frontal gyrus; ; yolk sac; ; hippocampus proper; ; left ventricle; ; cerebellar cortex; ; lip; ; spermatocyte; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium channel activity ; delayed rectifier potassium channel activity ; voltage-gated ion channel activity ; ion channel activity ; voltage-gated potassium channel activity ;
Cellular component	membrane ; voltage-gated potassium channel complex ; plasma membrane ; extracellular exosome ; integral component of membrane ;
Biological process	regulation of heart contraction ; regulation of insulin secretion ; regulation of ion transmembrane transport ; ion transport ; potassium ion transport ; transmembrane transport ; potassium ion transmembrane transport ; protein homooligomerization ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	26251
	240444
	ENSG00000178342
	ENSMUSG00000059852
	Q9UJ96
	n/a
	NM_012283
	NM_001190373
	NP_036415
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Potassium voltage-gated channel subfamily G member 2 is a protein that in humans is encoded by the KCNG2 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]^[6]

Related Research Articles

Potassium voltage-gated channel subfamily D member 3 also known as K_v4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current (I_to1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.

Potassium voltage-gated channel subfamily A member 6 also known as K_v1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily A member 7 also known as K_v1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. It may contribute to the cardiac transient outward potassium current (I_to1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Potassium voltage-gated channel subfamily A member 10 also known as K_v1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily C member 2 is a protein that in humans is encoded by the KCNC2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit (Kv3.2).

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 2 is a protein that in humans is encoded by the KCNV2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 4 is a protein that in humans is encoded by the KCNH4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000178342 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059852 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Zhu XR, Netzer R, Bohlke K, Liu Q, Pongs O (Dec 1999). "Structural and functional characterization of Kv6.2 a new gamma-subunit of voltage-gated potassium channel". Receptors Channels. 6 (5): 337–50. PMID 10551266.
1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

External links

Kv6.2+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
KCNB2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000178342 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059852 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10551266-5] 1 2 Zhu XR, Netzer R, Bohlke K, Liu Q, Pongs O (Dec 1999). "Structural and functional characterization of Kv6.2 a new gamma-subunit of voltage-gated potassium channel". Receptors Channels. 6 (5): 337–50. PMID 10551266.

[pmid16382104-6] 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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