CACNG4

Last updated
CACNG4
Identifiers
Aliases CACNG4 , calcium voltage-gated channel auxiliary subunit gamma 4
External IDs OMIM: 606404; MGI: 1859167; HomoloGene: 8674; GeneCards: CACNG4; OMA:CACNG4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

27092

54377

Ensembl

ENSG00000075461

ENSMUSG00000020723

UniProt

Q9UBN1

Q9JJV4

RefSeq (mRNA)

NM_014405

NM_019431

RefSeq (protein)

NP_055220

NP_062304

Location (UCSC) Chr 17: 66.96 – 67.03 Mb Chr 11: 107.62 – 107.69 Mb
PubMed search [3] [4]
Wikidata
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Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene. [5] [6]

Contents

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes. [6]

See also

Related Research Articles

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Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene.

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<span class="mw-page-title-main">CACNG1</span> Protein-coding gene in humans

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<span class="mw-page-title-main">CACNA2D2</span> Protein-coding gene in humans

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000075461 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020723 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Burgess DL, Davis CF, Gefrides LA, Noebels JL (Jan 2000). "Identification of Three Novel Ca2+ Channel γ Subunit Genes Reveals Molecular Diversification by Tandem and Chromosome Duplication". Genome Res. 9 (12): 1204–13. doi:10.1101/gr.9.12.1204. PMC   311002 . PMID   10613843.
  6. 1 2 "Entrez Gene: CACNG4 calcium channel, voltage-dependent, gamma subunit 4".

Further reading

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