KCNS2

KCNS2
Identifiers
Aliases	KCNS2 , KV9.2, potassium voltage-gated channel modifier subfamily S member 2
External IDs	OMIM: 602906 MGI: 1197011 HomoloGene: 22465 GeneCards: KCNS2
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q22.2 Start 98,426,958 bp [1] End 98,432,853 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 B3.1 Start 34,837,355 bp [2] End 34,843,407 bp [2]
Gene ontology Molecular function • ion channel activity • potassium channel activity • GO:0001948 protein binding • voltage-gated ion channel activity • voltage-gated potassium channel activity Cellular component • perinuclear region of cytoplasm • integral component of membrane • voltage-gated potassium channel complex • plasma membrane • membrane Biological process • potassium ion transport • regulation of ion transmembrane transport • regulation of delayed rectifier potassium channel activity • protein homooligomerization • ion transport • transmembrane transport • potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3788	16539
Ensembl	ENSG00000156486	ENSMUSG00000050963
UniProt	Q9ULS6	O35174
RefSeq (mRNA)	NM_020697	NM_001271704 NM_181317
RefSeq (protein)	NP_065748	NP_001258633 NP_851834
Location (UCSC)	Chr 8: 98.43 – 98.43 Mb	Chr 15: 34.84 – 34.84 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene. ^{[5] [6]} The protein encoded by this gene is a voltage-gated potassium channel subunit. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000156486 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050963 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M (Oct 1997). "New modulatory alpha subunits for mammalian Shab K+ channels". J Biol Chem. 272 (39): 24371–9. doi: 10.1074/jbc.272.39.24371 . PMID   9305895.
6. Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID   16382104. S2CID   219195192.

Further reading

• Banfi S, Borsani G, Rossi E, et al. (1996). "Identification and mapping of human cDNAs homologous to Drosophila mutant genes through EST database searching". Nat. Genet. 13 (2): 167–74. doi:10.1038/ng0696-167. PMID   8640222. S2CID   38441640.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hirosawa M, Nagase T, Ishikawa K, et al. (1999). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi: 10.1093/dnares/6.5.329 . PMID   10574461.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• Kv9.2+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
• KCNS2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)