Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene. [5] [6] [7] [8]
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain. [8]
HCN1 channel expression is found in the sinoatrial node, [9] [10] the neocortex, hippocampus, cerebellar cortex, dorsal root ganglion, trigeminal ganglion and brainstem. [11] [12] [13] [14] [15]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.