CLIC3

CLIC3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3FY7, 3KJY
Identifiers
Aliases	CLIC3 , chloride intracellular channel 3
External IDs	OMIM: 606533; MGI: 1916704; HomoloGene: 3432; GeneCards: CLIC3; OMA:CLIC3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,996,568 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	25,348,788 bp
RNA expression pattern
	Top expressed in
	oral cavity; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; skin of abdomen; ; skin of leg; ; granulocyte; ; mucosa of pharynx; ; right lung; ; gums; ; placenta;
	Top expressed in
	lip; ; esophagus; ; right lung lobe; ; left lung; ; left lung lobe; ; corneal stroma; ; skin of external ear; ; skin of back; ; skin of abdomen; ; belly cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; voltage-gated ion channel activity ; chloride channel activity ; glutathione transferase activity ;
Cellular component	cytoplasm ; integral component of membrane ; extracellular exosome ; membrane ; nucleus ; chloride channel complex ; nuclear body ;
Biological process	regulation of ion transmembrane transport ; chloride transport ; ion transport ; signal transduction ; chloride transmembrane transport ; glutathione metabolic process ; transport ; ion transmembrane transport ;
	Sources:Amigo / QuickGO
Orthologs
	9022
	69454
	ENSG00000169583
	ENSMUSG00000015093
	O95833
	Q9D7P7
	NM_004669
	NM_027085
	NP_004660
	NP_081361
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated July 17, 2024

Chloride intracellular channel protein 3 is a protein that in humans is encoded by the CLIC3 gene.^[5] This protein is a chloride channel.^[5]

Related Research Articles

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Chloride channel accessory 2 is a protein that in humans is encoded by the CLCA2 gene.

Chloride intracellular channel protein 2 is a protein that in humans is encoded by the CLIC2 gene.

Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene.

Potassium-chloride transporter, member 4 is a chloride potassium symporter protein. It is encoded by the gene SLC12A4.

K_v channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene.

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 is an enzyme that in humans is encoded by the B3GAT3 gene.

Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene.

Chloride intracellular channel protein 5 is a protein that in humans is encoded by the CLIC5 gene.

Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.

Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 is an enzyme that in humans is encoded by the HS3ST3A1 gene.

Chloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.

Protein orai-2 is a protein that in humans is encoded by the ORAI2 gene.

Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000169583 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000015093 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Qian Z, Okuhara D, Abe MK, Rosner MR (Feb 1999). "Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel". J Biol Chem. 274 (3): 1621–7. doi: 10.1074/jbc.274.3.1621 . PMID 9880541.

External links

CLIC3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human CLIC3 genome location and CLIC3 gene details page in the UCSC Genome Browser .
Overview of all the structural information available in the PDB for UniProt : O95833 (Human Chloride intracellular channel protein 3 (CLIC3)) at the PDBe-KB .

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000169583 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000015093 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9880541-5] 1 2 Qian Z, Okuhara D, Abe MK, Rosner MR (Feb 1999). "Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel". J Biol Chem. 274 (3): 1621–7. doi: 10.1074/jbc.274.3.1621 . PMID 9880541.

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CLIC3

Contents

See also

Related Research Articles

References

Further reading

External links