KCNK6 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | KCNK6 , K2p6.1, KCNK8, TOSS, TWIK-2, TWIK2, potassium two pore domain channel subfamily K member 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603939; MGI: 1891291; HomoloGene: 31266; GeneCards: KCNK6; OMA:KCNK6 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Potassium channel subfamily K member 6 is a protein encoded by the KCNK6 gene in humans. [5] [6] [7] [8]
This gene encodes K2P6.1, a member of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P6.1, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics. [8]
Disks large homolog 3 (DLG3) also known as neuroendocrine-DLG or synapse-associated protein 102 (SAP-102) is a protein that in humans is encoded by the DLG3 gene. DLG3 is a member of the membrane-associated guanylate kinase (MAGUK) superfamily of proteins.
Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.
G protein-activated inward rectifier potassium channel 2 is a protein that in humans is encoded by the KCNJ6 gene. Mutation in KCNJ6 gene has been proposed to be the cause of Keppen-Lubinsky Syndrome (KPLBS).
Potassium inwardly-rectifying channel, subfamily J, member 4, also known as KCNJ4 or Kir2.3, is a human gene.
Potassium inwardly-rectifying channel, subfamily J, member 8, also known as KCNJ8, is a human gene encoding the Kir6.1 protein. A mutation in KCNJ8 has been associated with cardiac arrest in the early repolarization syndrome.
Potassium channel subfamily K member 2, also known as TREK-1, is a protein that in humans is encoded by the KCNK2 gene.
G protein-activated inward rectifier potassium channel 1(GIRK-1) is encoded in the human by the gene KCNJ3.
Potassium channel subfamily K member 3 is a protein that in humans is encoded by the KCNK3 gene.
Voltage-gated potassium channel subunit beta-1 is a protein that in humans is encoded by the KCNAB1 gene.
Potassium channel subfamily K member 1 is a protein that in humans is encoded by the KCNK1 gene.
Sodium/potassium-transporting ATPase gamma chain is a protein that in humans is encoded by the FXYD2 gene.
Calcium-activated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNMB2 gene.
Potassium inwardly-rectifying channel, subfamily J, member 16 (KCNJ16) is a human gene encoding the Kir5.1 protein.
Potassium channel subfamily K member 5 is a protein that in humans is encoded by the KCNK5 gene.
Calcium-activated potassium channel subunit beta-4 is a protein that in humans is encoded by the KCNMB4 gene.
G protein-activated inward rectifier potassium channel 3 is a protein that in humans is encoded by the KCNJ9 gene.
Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.
Potassium channel, subfamily K, member 7, also known as KCNK7 or K2P7.1 is a protein which is encoded in humans by the KCNK7 gene. K2P7.1 is a potassium channel containing two pore-forming P domains. Multiple transcript variants encoding different isoforms have been found for this gene.
Potassium channel, subfamily K, member 12, also known as KCNK12 is a human gene. The protein encoded by this gene, K2P12.1, is a potassium channel containing two pore-forming P domains.
Potassium channel subfamily K member 18 (KCNK18), also known as TWIK-related spinal cord potassium channel (TRESK) or K2P18.1 is a protein that in humans is encoded by the KCNK18 gene. K2P18.1 is a potassium channel containing two pore-forming P domains.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.