KCNG4

KCNG4
Identifiers
Aliases	KCNG4 , KV6.3, KV6.4, potassium voltage-gated channel modifier subfamily G member 4
External IDs	OMIM: 607603 MGI: 1913983 HomoloGene: 23553 GeneCards: KCNG4
Gene location (Human)
Chr.	Chromosome 16 (human)
End	84,240,012 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	120,362,419 bp
RNA expression pattern
	Top expressed in
	amygdala; ; substantia nigra; ; hypothalamus; ; prefrontal cortex; ; hippocampus proper; ; putamen; ; nucleus accumbens; ; caudate nucleus; ; dorsolateral prefrontal cortex; ; cerebellum;
	Top expressed in
	facial motor nucleus; ; cerebellar cortex; ; knee joint; ; vastus lateralis muscle; ; habenula; ; triceps brachii muscle; ; temporal muscle; ; cerebellar vermis; ; anterior horn of spinal cord; ; tibialis anterior muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity ; ion channel activity ; potassium channel activity ; delayed rectifier potassium channel activity ; transmembrane transporter binding ; voltage-gated ion channel activity ;
Cellular component	integral component of membrane ; voltage-gated potassium channel complex ; plasma membrane ; membrane ;
Biological process	potassium ion transport ; regulation of ion transmembrane transport ; protein homooligomerization ; ion transport ; transmembrane transport ; potassium ion transmembrane transport ;
	Sources:Amigo / QuickGO
Orthologs
	93107
	66733
	ENSG00000168418
	ENSMUSG00000045246
	Q8TDN1
	Q80XM3
	NM_172347 ; NM_133490
	NM_025734 ; NM_001357210
	NP_758857
	NP_080010 ; NP_001344139
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 29, 2022

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[6]

Related Research Articles

Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene. It contributes to the cardiac transient outward potassium current (I_to1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene.

Voltage-gated potassium channel subunit beta-1 is a protein that in humans is encoded by the KCNAB1 gene.

Calcium-activated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNMB2 gene.

Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the K_v10.2 protein.

Kv channel-interacting protein 4 is a protein that in humans is encoded by the KCNIP4 gene.

Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.

Potassium voltage-gated channel subfamily A member 6 also known as K_v1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily A member 10 also known as K_v1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 2 is a protein that in humans is encoded by the KCNV2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Voltage-gated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNAB3 gene. The protein encoded by this gene is a voltage-gated potassium channel beta subunit.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000168418 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045246 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A. 99 (12): 7986–91. Bibcode:2002PNAS...99.7986O. doi: 10.1073/pnas.122617999 . PMC 123007 . PMID 12060745.
1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

External links

Kv6.4+Potassium+Channel at the US National Library of Medicine Medical Subject Headings (MeSH)
KCNG4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000168418 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045246 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12060745-5] Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ (Jun 2002). "Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome". Proc Natl Acad Sci U S A. 99 (12): 7986–91. Bibcode:2002PNAS...99.7986O. doi: 10.1073/pnas.122617999 . PMC 123007 . PMID 12060745.

[pmid16382104-6] 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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KCNG4

Contents

Related Research Articles

References

Further reading

External links