KCNS1

KCNS1
Identifiers
Aliases	KCNS1 , KV9.1, potassium voltage-gated channel modifier subfamily S member 1
External IDs	OMIM: 602905 MGI: 1197019 HomoloGene: 20517 GeneCards: KCNS1
Gene location (Human)
Chr.	Chromosome 20 (human)
End	45,101,127 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	164,013,033 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; cardia; ; Brodmann area 46; ; superior frontal gyrus; ; postcentral gyrus; ; orbitofrontal cortex; ; spinal ganglia; ; ventral tegmental area; ; superior vestibular nucleus;
	Top expressed in
	parotid gland; ; superior frontal gyrus; ; calvaria; ; entorhinal cortex; ; primary motor cortex; ; hippocampus proper; ; lip; ; esophagus; ; quadriceps femoris muscle; ; striated muscle tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated potassium channel activity ; ion channel activity ; potassium channel regulator activity ; potassium channel activity ; protein binding ; delayed rectifier potassium channel activity ; voltage-gated ion channel activity ;
Cellular component	integral component of membrane ; membrane ; voltage-gated potassium channel complex ; plasma membrane ; perinuclear region of cytoplasm ;
Biological process	regulation of ion transmembrane transport ; protein homooligomerization ; ion transport ; transmembrane transport ; potassium ion transmembrane transport ; regulation of delayed rectifier potassium channel activity ; potassium ion transport ;
	Sources:Amigo / QuickGO
Orthologs
	3787
	16538
	ENSG00000124134
	ENSMUSG00000040164
	Q96KK3
	O35173
	NM_002251 ; NM_001322799
	NM_008435
	NP_001309728 ; NP_002242
	NP_032461
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 04, 2024

Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene.^[5]^[6] The protein encoded by this gene is a voltage-gated potassium channel subunit.^[5]^[6]

Related Research Articles

Potassium voltage-gated channel subfamily KQT member 5 is a protein that in humans is encoded by the KCNQ5 gene.

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as K_v3.4, is a human gene.

Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the K_v10.2 protein.

Kv channel-interacting protein 4 is a protein that in humans is encoded by the KCNIP4 gene.

Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene.

Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.

Potassium voltage-gated channel subfamily A member 6 also known as K_v1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily A member 7 also known as K_v1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. It may contribute to the cardiac transient outward potassium current (I_to1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Potassium voltage-gated channel subfamily A member 10 also known as K_v1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily V member 2 is a protein that in humans is encoded by the KCNV2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.

Voltage-gated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNAB3 gene. The protein encoded by this gene is a voltage-gated potassium channel beta subunit.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000124134 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040164 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M (Oct 1997). "New modulatory alpha subunits for mammalian Shab K+ channels". J Biol Chem. 272 (39): 24371–9. doi: 10.1074/jbc.272.39.24371 . PMID 9305895.
1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

External links

Kv9.1+Potassium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
KCNS1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000124134 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040164 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9305895-5] 1 2 Salinas M, Duprat F, Heurteaux C, Hugnot JP, Lazdunski M (Oct 1997). "New modulatory alpha subunits for mammalian Shab K+ channels". J Biol Chem. 272 (39): 24371–9. doi: 10.1074/jbc.272.39.24371 . PMID 9305895.

[pmid16382104-6] 1 2 Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W, Wang X (Dec 2005). "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels". Pharmacol Rev. 57 (4): 473–508. doi:10.1124/pr.57.4.10. PMID 16382104. S2CID 219195192.

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KCNS1

Contents

Related Research Articles

References

Further reading

External links