![<span class="mw-page-title-main">Estradiol valerate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Estradiol_valerate.svg/320px-Estradiol_valerate.svg.png)
Estradiol valerate (EV), sold for use by mouth under the brand name Progynova and for use by injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen medication. It is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender people, and in hormonal birth control. It is also used in the treatment of prostate cancer. The medication is taken by mouth or by injection into muscle or fat once every 1 to 4 weeks.
![<span class="mw-page-title-main">Estradiol benzoate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/0/0d/Estradiol_benzoate.svg/320px-Estradiol_benzoate.svg.png)
Estradiol benzoate (EB), sold under the brand name Progynon-B among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for transgender women, and in the treatment of gynecological disorders. It is also used in the treatment of prostate cancer in men. Estradiol benzoate is used in veterinary medicine as well. When used clinically, the medication is given by injection into muscle usually two to three times per week.
![<span class="mw-page-title-main">Estradiol cypionate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Estradiol_17_beta-cypionate.svg/320px-Estradiol_17_beta-cypionate.svg.png)
Estradiol cypionate (EC), sold under the brand name Depo-Estradiol among others, is an estrogen medication which is used in hormone therapy for menopausal symptoms and low estrogen levels in women, in hormone therapy for trans women, and in hormonal birth control for women. It is given by injection into muscle once every 1 to 4 weeks.
![<span class="mw-page-title-main">Estradiol undecylate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/f/f1/Estradiol_undecylate.svg/320px-Estradiol_undecylate.svg.png)
Estradiol undecylate, also known as estradiol undecanoate and formerly sold under the brand names Delestrec and Progynon Depot 100 among others, is an estrogen medication which has been used in the treatment of prostate cancer in men. It has also been used as a part of hormone therapy for transgender women. Although estradiol undecylate has been used in the past, it was discontinued and hence is no longer available. The medication has been given by injection into muscle usually once a month.
![<span class="mw-page-title-main">Hydroxyprogesterone heptanoate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/f/f4/Hydroxyprogesterone_heptanoate.svg/320px-Hydroxyprogesterone_heptanoate.svg.png)
Hydroxyprogesterone heptanoate (OHPH), also known as hydroxyprogesterone enanthate (OHPE) and sold under the brand names H.O.P., Lutogil A.P., and Lutogyl A.P. among others, is a progestin medication used for progestogenic indications. It has been formulated both alone and in together with estrogens, androgens/anabolic steroids, and other progestogens in several combination preparations. OHPH is given by injection into muscle at regular intervals.
![<span class="mw-page-title-main">Testosterone isobutyrate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/0/0d/Testosterone_isobutyrate.svg/320px-Testosterone_isobutyrate.svg.png)
Testosterone isobutyrate, sold under the brand names Agovirin-Depot and Perandren M among others, is an androgen and anabolic steroid medication and a testosterone ester which is used for indications such as low testosterone levels in men and delayed puberty in boys. It is available only in the Czech Republic and Slovakia. The medication is administered by injection into muscle once every 1 to 2 weeks in males. Unlike most other testosterone esters, which are provided as oil solutions, testosterone isobutyrate is formulated as a microcrystalline aqueous suspension.
![<span class="mw-page-title-main">Prasterone enanthate</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/6/68/Prasterone_enanthate.svg/320px-Prasterone_enanthate.svg.png)
Prasterone enanthate, also known as dehydroepiandrosterone enanthate (DHEA-E) and sold in combination with estradiol valerate under the brand name Gynodian Depot among others, is a weak androgen, estrogen, and neurosteroid medication which is used as a component of menopausal hormone therapy to treat menopausal symptoms in women. It is available only as an injectable preparation in combination with estradiol valerate. The medication is given by injection into muscle typically once every 4 weeks.
![<span class="mw-page-title-main">Testosterone enantate benzilic acid hydrazone</span> Chemical compound](https://upload.wikimedia.org/wikipedia/commons/thumb/6/60/Testosterone_enanthate_benziloylhydrazone.svg/320px-Testosterone_enanthate_benziloylhydrazone.svg.png)
Testosterone enantate benzilic acid hydrazone (TEBH), or testosterone 17β-enantate 3-benzilic acid hydrazone, is a synthetic, injected androgen/anabolic steroid and an androgen ester – specifically, the C17β enantate (heptanoate) ester and C3 benzilic acid hydrazone of testosterone. It was previously marketed in combination with estradiol benzoate and estradiol dienantate under the brand names Climacteron, Lactimex, and Lactostat. Clinical studies have assessed this formulation. TEBH was first described in the scientific literature in 1959. It is a very long-lasting prodrug of testosterone when administered in oil via intramuscular injection.
![<span class="mw-page-title-main">Estradiol benzoate/estradiol dienanthate/testosterone enanthate benzilic acid hydrazone</span> Combination drug](https://upload.wikimedia.org/wikipedia/commons/thumb/7/74/Estradiol_and_testosterone_levels_after_an_intramuscular_injection_of_Climacteron_in_women.png/320px-Estradiol_and_testosterone_levels_after_an_intramuscular_injection_of_Climacteron_in_women.png)
Estradiol benzoate/estradiol dienanthate/testosterone enanthate benzilic acid hydrazone (EB/EDE/TEBH), sold under the brand names Climacteron, Lactimex, Lactostat, and Amenose, is an injectable combination medication of estradiol benzoate (EB), an estrogen, estradiol dienanthate (EDE), an estrogen, and testosterone enanthate benzilic acid hydrazone (TEBH), an androgen/anabolic steroid, which is used in menopausal hormone therapy for peri- and postmenopausal women and to suppress lactation in postpartum women. Clinical studies have assessed this formulation.
![<span class="mw-page-title-main">Estradiol benzoate/estradiol phenylpropionate</span> Combination drug](https://upload.wikimedia.org/wikipedia/commons/thumb/0/0d/Estradiol_benzoate.svg/320px-Estradiol_benzoate.svg.png)
Estradiol benzoate/estradiol phenylpropionate (EB/EPP), sold under the brand name Dimenformon Prolongatum, is an injectable combination formulation of estradiol benzoate (EB), a shorter-acting estrogen, and estradiol phenylpropionate (EPP), a longer-acting estrogen, which has been used in menopausal hormone therapy for women in Europe but appears to no longer be available. It has also been used to suppress lactation in women and has been used in feminizing hormone therapy for transgender women. It has been provided in the form of 1 mL ampoules containing 2.5 mg EB and 10 mg EPP in oil solution and is administered by intramuscular injection at regular intervals.
![<span class="mw-page-title-main">Estradiol valerate/testosterone enanthate</span> Combination drug](https://upload.wikimedia.org/wikipedia/commons/thumb/6/66/Estradiol_valerate.svg/320px-Estradiol_valerate.svg.png)
Estradiol valerate/testosterone enanthate (EV/TE), sold under the brand names Primodian Depot and Ditate among others, is an injectable combination medication of estradiol valerate (EV), an estrogen, and testosterone enanthate (TE), an androgen/anabolic steroid, which is used in menopausal hormone therapy for women. The medication is also used to suppress lactation in postpartum women.
Estradiol benzoate/estradiol phenylpropionate/testosterone propionate/testosterone phenylpropionate/testosterone isocaproate (EB/EPP/TP/TPP/TiC), sold under the brand names Estandron Prolongatum, Lynandron Prolongatum, and Mixogen, was an injectable combination medication of the estrogens estradiol benzoate (EB) and estradiol phenylpropionate (EPP) and the androgens/anabolic steroids testosterone propionate (TP), testosterone phenylpropionate (TPP), and testosterone isocaproate (TiC) which was used in menopausal hormone therapy for women. It was also used to suppress lactation in postpartum women.
![<span class="mw-page-title-main">Estradiol/estradiol enanthate</span> Combination drug](https://upload.wikimedia.org/wikipedia/commons/thumb/0/00/Estradiol.svg/320px-Estradiol.svg.png)
Estradiol/estradiol enanthate (E2/E2-EN) is an injectable combination formulation of estradiol (E2), a short-acting estrogen, and estradiol enanthate (E2-EN), a long-acting estrogen, which was developed by Boehringer around 1960 for potential medical use but was never marketed. It contained 1 mg E2 and 9 mg E2-EN in oil solution and was intended for administration by intramuscular injection.
![<span class="mw-page-title-main">Estradiol cypionate/testosterone enanthate</span> Combination drug](https://upload.wikimedia.org/wikipedia/commons/thumb/8/8d/Estradiol_17_beta-cypionate.svg/320px-Estradiol_17_beta-cypionate.svg.png)
Estradiol cypionate/testosterone enanthate (EC/TE), sold under the brand name Supligol, is an injectable combination medication of estradiol cypionate (EC), an estrogen, and testosterone enanthate (TE), an androgen/anabolic steroid, which is used in menopausal hormone therapy for women, to treat prostatic hypertrophy in men, to treat osteoporosis, and to suppress lactation in women, among other uses. It contains 4 mg EC and 80 mg TE in oil solution in each ampoule and is administered by intramuscular injection once every 3 to 6 weeks for hormone therapy in women. The medication was marketed by 1976 and remains available today in Paraguay.
Estradiol benzoate/estradiol valerate/norethisterone acetate/testosterone enanthate (EB/EV/NETA/TE), sold under the brand name Ablacton, is an injectable combination medication of estradiol benzoate (EB), an estrogen, estradiol valerate (EV), an estrogen, norethisterone acetate (NETA), a progestin, and testosterone enanthate (TE), an androgen/anabolic steroid, which has been used to suppress lactation in women. It contains 5 mg EB, 8 mg EV, 20 mg NETA, and 180 mg TE in oil solution and is provided in the form of ampoules. It is given as a single intramuscular injection following childbirth. The medication was manufactured by Schering and was previously marketed in Italy and Spain, but is no longer available.
Estradiol diundecylate/hydroxyprogesterone heptanoate/testosterone cyclohexylpropionate (EDU/OHPH/TCHP), sold under the brand name Trioestrine Retard, is an injectable combination medication of estradiol diundecylate (EDU), an estrogen, hydroxyprogesterone heptanoate (OHPH), a progestogen, and testosterone cyclohexylpropionate (TCHP), an androgen/anabolic steroid. It contained 2.25 mg EDU, 100 mg OHPH, and 67.5 mg TCHP in oil solution, was provided as ampoules, and was administered by intramuscular injection. The medication was manufactured by Roussel and Théramex and was marketed by 1953. It is no longer available.
Estradiol dibutyrate/hydroxyprogesterone heptanoate/testosterone caproate (EDBu/OHPH/TCa), sold under the brand name Triormon Depositum, is an injectable combination medication of estradiol dibutyrate (EDBu), an estrogen, hydroxyprogesterone heptanoate (OHPH), a progestogen, and testosterone caproate (TCa), an androgen/anabolic steroid, which was used in the treatment of menopausal symptoms in women. It contained 3 mg EDBu, 30 mg OHPH, and 50 mg TCa in oil solution and was administered by intramuscular injection. The medication was developed by 1957. It is no longer available.