CD320

CD320
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZRP
Identifiers
Aliases	CD320 , 8D6, 8D6A, TCBLR, CD320 molecule, TCN2R
External IDs	OMIM: 606475 MGI: 1860083 HomoloGene: 9573 GeneCards: CD320
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.2 Start 8,302,127 bp [1] End 8,308,358 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17 B1|17 17.98 cM Start 34,062,065 bp [2] End 34,068,748 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen body of stomach right lobe of thyroid gland Left adrenal gland left coronary artery fundus thoracic aorta ascending aorta body of pancreas left lobe of thyroid gland Top expressed in spermatocyte spermatid seminiferous tubule morula parotid gland Epithelium of stomach proximal tubule medial ganglionic eminence otic placode white adipose tissue More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cobalamin binding growth factor activity ABC-type vitamin B12 transporter activity protein binding calcium ion binding metal ion binding Cellular component integral component of membrane endosome membrane endoplasmic reticulum membrane extracellular exosome integral component of plasma membrane plasma membrane Biological process cobalamin metabolic process regulation of vitamin metabolic process cobalamin transport positive regulation of B cell proliferation B cell costimulation regulation of signaling receptor activity signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51293 54219 Ensembl ENSG00000167775 ENSMUSG00000002308 UniProt Q9NPF0 Q9Z1P5 RefSeq (mRNA) NM_016579 NM_001165895 NM_019421 NM_001305169 RefSeq (protein) NP_001159367 NP_057663 NP_001292098 NP_062294 Location (UCSC) Chr 19: 8.3 – 8.31 Mb Chr 17: 34.06 – 34.07 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

CD320 (cluster of differentiation 320) is a human gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000167775 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002308 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: CD320 CD320 molecule".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Li L, Zhang X, Kovacic S, et al. (2000). "Identification of a Human Follicular Dendritic Cell Molecule That Stimulates Germinal Center B Cell Growth". J. Exp. Med. 191 (6): 1077–84. doi:10.1084/jem.191.6.1077. PMC   2193124 . PMID   10727470.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Acierno JS, Kennedy JC, Falardeau JL, et al. (2001). "A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2". Genomics. 73 (2): 203–10. doi:10.1006/geno.2001.6526. PMID   11318610.
• Zhang X, Li L, Jung J, et al. (2001). "The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation". J. Immunol. 167 (1): 49–56. doi: 10.4049/jimmunol.167.1.49 . PMID   11418631.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• CD320+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• Human CD320 genome location and CD320 gene details page in the UCSC Genome Browser .
• Overview of all the structural information available in the PDB for UniProt : Q9NPF0 (Human CD320 antigen) at the PDBe-KB .