CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. [5] [6]
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. [5]
Certain alleles of this gene may be associated with susceptibility to multiple sclerosis. [7] [8]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.