Aquaporin-7

Last updated
AQP7
Identifiers
Aliases AQP7 , AQP7L, AQP9, AQPap, GLYCQTL, aquaporin 7
External IDs OMIM: 602974; MGI: 1314647; HomoloGene: 48000; GeneCards: AQP7; OMA:AQP7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007473

RefSeq (protein)
Location (UCSC) Chr 9: 33.38 – 33.4 Mb Chr 4: 41.03 – 41.05 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Aquaporin-7 (AQP-7) is a protein that in humans is encoded by the AQP7 gene. [5] [6]

Contents

Aquaporins/major intrinsic proteins (MIP) are a family of water-selective membrane channels. Aquaporin-7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin-7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin-7 facilitates water, glycerol and urea transport. It may play an important role in thermoregulation in the form of perspiration, and sperm function. [6]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000165269 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028427 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S (Sep 1997). "Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea". J Biol Chem. 272 (33): 20782–6. doi: 10.1074/jbc.272.33.20782 . PMID   9252401.
  6. 1 2 "Entrez Gene: AQP7 aquaporin 7".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.