AQP7 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | AQP7 , AQP7L, AQP9, AQPap, GLYCQTL, aquaporin 7 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602974; MGI: 1314647; HomoloGene: 48000; GeneCards: AQP7; OMA:AQP7 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aquaporin-7 (AQP-7) is a protein that in humans is encoded by the AQP7 gene. [5] [6]
Aquaporins/major intrinsic proteins (MIP) are a family of water-selective membrane channels. Aquaporin-7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin-7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin-7 facilitates water, glycerol and urea transport. It may play an important role in thermoregulation in the form of perspiration, and sperm function. [6]
Aldolase A, also known as fructose-bisphosphate aldolase, is an enzyme that in humans is encoded by the ALDOA gene on chromosome 16.
The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules.
Aquaporin 3 (AQP-3) is the protein product of the human AQP3 gene. It is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. Aquaporin-3 is also permeable to glycerol, ammonia, urea, and hydrogen peroxide. It is expressed in various tissues including the skin, respiratory tract, and kidneys as well as various types of cancers. In the kidney, aquaproin-3 is unresponsive to the antidiuretic hormone vasopressin, unlike aquaporin-2. This protein is also a determinant for the GIL blood group system.
DNA replication licensing factor MCM7 is a protein that in humans is encoded by the MCM7 gene.
Hypoxia-inducible factor 3 alpha is a protein that in humans is encoded by the HIF3A gene.
G-protein coupled receptor 39 is a protein that in humans is encoded by the GPR39 gene.
Glutamate-cysteine ligase regulatory subunit is an enzyme that in humans is encoded by the GCLM gene.
Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.
Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.
Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT6 gene.
Lathosterol oxidase is a Δ7-sterol 5(6)-desaturase enzyme that in humans is encoded by the SC5D gene.
Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene.
Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene.
ATP synthase subunit b, mitochondrial is an enzyme that in humans is encoded by the ATP5PB gene.
Kallikrein-15 is a protein that in humans is encoded by the KLK15 gene.
Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene.
The ATP5MC2 gene is one of three human paralogs that encode membrane subunit c of the mitochondrial ATP synthase.
Solute carrier family 2, facilitated glucose transporter member 12 is a protein that in humans is encoded by the SLC2A12 gene.
Coiled-coil domain-containing protein 80 is a protein that in humans is encoded by the CCDC80 gene. Bioinformatics analysis suggests the CCDC80 protein is a peroxiredoxin.
Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family. Its former designation KKLF stands for kidney-enriched Krüppel-like factor.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.