Salt water aspiration syndrome

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Salt water aspiration syndrome
Compensacion.jpg
Aspiration of salt water due to diving equipment malfunction or improper breathing techniques can go unnoticed, as the small size of water droplets may not trigger the upper airway's cough reflex.
Specialty Undersea medicine

Salt water aspiration syndrome or saltwater aspiration syndrome is a medical condition caused by the inhalation or aspiration (entry of materials into lungs from mouth) of small amounts of salt water during an underwater dive, leading to lung irritation and inflammation. Unlike drowning or near-drowning, it does not involve ingestion of large volumes of water. It often results from faulty diving equipment or improper breathing techniques, allowing fine water droplets to reach the lower respiratory tract.

Contents

The condition begins with a cough, followed by shortness of breath, chest discomfort or pain, shivering, fever and other systemic symptoms. It can resemble a viral infection but improves within hours, especially with supplemental oxygen. While most cases resolve on their own, severe instances may require critical care. Diagnosis is based on clinical history and symptom progression. Salt water aspiration syndrome was first described in 1970.

Cause and mechanism

Salt water aspiration syndrome occurs when small amounts of salt water are inhaled or aspirated, unlike drowning and near-drowning which involve intake of large volumes of water. This condition can develop subtly over the course of an underwater dive [1] or happen with a single aspiration event. [2] Faulty diving equipment such as diving regulators, improper breathing techniques, or buddy breathing lead to the inhalation or aspiration of fine salt water droplets. The small size of the droplets allows them to reach the lower respiratory tract without significantly triggering the upper airway's cough reflex, hence getting aspirated without causing immediate symptoms during the dive. [1]

Hypertonic salt water—being more concentrated than human blood—creates an osmotic gradient when it enters the lungs. This gradient draws water out of surrounding lung tissues into the alveoli and bronchioles, leading to irritation and inflammation. Salt water can also cause oxidative stress, dilution of pulmonary surfactant, breakdown of the blood-air barrier, cellular degradation and cell death. [3] Marine microorganisms and particulates can further exacerbate inflammatory processes, which may cause or contribute towards systemic symptoms seen with this condition. [4]

Clinical presentation

Salt water aspiration syndrome chest x-ray, before treatment.png
Acute pulmonary edema due to salt water aspiration syndrome
Salt water aspiration syndrome chest x-ray, after treatment.png
Recovery after 48 hours of supplemental oxygen
Chest x-rays of a 61 year-old female who developed salt water aspiration syndrome while swimming during a triathlon. [5]

Most patients with salt water aspiration syndrome report experiencing aspiration during their dive. Affected individuals start with a cough immediately after completing the dive, [A] sometimes productive of excessive or blood-tinged sputum. [1] Following a latency period of about two hours, divers may develop shortness of breath, increased respiratory rate, increased heart rate, bluish skin, chest discomfort and pain. [6]

The condition generally mimics symptoms of a viral infection. Fever, malaise and chills are most commonly reported, and usually the first systemic symptoms to appear. Most individuals experience tremors and shivering [1] — the latter is worse with reduced oxygen levels in blood. [7] These symptoms tend to worsen with cold exposure or physical activity. Headaches are reported in about two-thirds of cases, while about one-third experience body aches. Gastrointestinal involvement can cause loss of appetite, nausea and vomiting. Less commonly, affected individuals experience fainting, temporary loss of consciousness and mild confusion. [1] In rare cases, severe inflammation of lungs can occur. [2]

Lung auscultation may reveal abnormal breath sounds such as rhonchi (snoring-like) or crackles (rattling), and chest imaging can show lung consolidations [4] and edema. [5] Decreased lung volumes, including a reduction of average 0.7 liters in forced expiratory volume in 1 second and vital capacity, is found on spirometry. Laboratory studies do not show specific abnormalities, but low oxygen levels in blood, slightly elevated white blood cell count and lactate dehydrogenase levels may be seen. [1]

Diagnosis and treatment

The diagnosis of salt water aspiration syndrome is based on medical history and physical examination. Its initial symptoms of cough and difficulty breathing are similar to near-drowning, however, near-drowning does not cause viral infection-like symptoms. Furthermore, it can be difficult to distinguish the condition from an acute viral infection at first; unlike viral illnesses, salt water aspiration syndrome tends to improve within a few hours. [1]

The condition shares features with decompression sickness; a review of the dive profile and the absence of other symptoms associated with decompression can help distinguish between the two. [B] Significant improvement following supplemental oxygen further supports the diagnosis of salt water aspiration syndrome. [C] Other diving conditions like pulmonary barotrauma, immersion pulmonary edema and low body temperatures can produce similar symptoms or occur alongside this syndrome; these can be distinguished through the clinical course and imaging results. [1]

Treatment involves supportive care with supplemental oxygen, observation and rest. [1] Most cases resolve within the first 24 hours, often spontaneously without treatment. [10] Critical care may be necessary for severe cases or cases complicated with underlying respiratory disorders. [2]

Research

The audience member aspirated salt water that was splashed by a beluga whale; this led to severe inflammation of lungs and low oxygen levels in blood. Delphinapterus leucas in shallows.jpg
The audience member aspirated salt water that was splashed by a beluga whale; this led to severe inflammation of lungs and low oxygen levels in blood.

The condition was first described in 1970 by Carl Edmonds, [4] who documented 30 cases at the Royal Australian Navy's HMAS Penguin. [6] A 1989 study estimated that 37 percent of deaths that occurred during recreational scuba diving in Australia and New Zealand in the 1980s involved salt water aspiration syndrome. The study hypothesized—based on reports of the victim's symptoms and an analysis of their equipment—that the syndrome acted as an intermediate factor, exacerbating panic and exhaustion, which subsequently led to loss of consciousness and death by drowning. [11] In 2019, a case study reported severe salt water aspiration syndrome caused by a beluga whale splash in an audience member during a show at Georgia Aquarium which required critical care. [2]

See also

Notes

  1. Likely a cough reflex triggered by irritation of the lower airways, [4] which is suppressed during the dive due to unclear reasons. [1]
  2. A dive profile with decompression stops and slow gradual ascent would be less likely to cause decompression sickness. [8] Additionally, short duration and depth of dives would be less likely to cause decompression sickness. [6]
  3. In contrast, decompression sickness shows significant improvement with hyperbaric oxygen therapy, whereas supplemental oxygen only helps to stabilize the affected individual. [9]

Related Research Articles

<span class="mw-page-title-main">Hypoxia (medicine)</span> Medical condition of lack of oxygen in the tissues

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Although hypoxia is often a pathological condition, variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise.

<span class="mw-page-title-main">Pneumonia</span> Inflammation of the alveoli of the lungs

Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable.

<span class="mw-page-title-main">Cough</span> Sudden expulsion of air from the lungs as a reflex to clear irritants

A cough is a sudden expulsion of air through the large breathing passages which can help clear them of fluids, irritants, foreign particles and microbes. As a protective reflex, coughing can be repetitive with the cough reflex following three phases: an inhalation, a forced exhalation against a closed glottis, and a violent release of air from the lungs following opening of the glottis, usually accompanied by a distinctive sound.

<span class="mw-page-title-main">Air embolism</span> Vascular blockage by air bubbles

An air embolism, also known as a gas embolism, is a blood vessel blockage caused by one or more bubbles of air or other gas in the circulatory system. Air can be introduced into the circulation during surgical procedures, lung over-expansion injury, decompression, and a few other causes. In flora, air embolisms may also occur in the xylem of vascular plants, especially when suffering from water stress.

<span class="mw-page-title-main">Oxygen toxicity</span> Toxic effects of breathing oxygen at high partial pressures

Oxygen toxicity is a condition resulting from the harmful effects of breathing molecular oxygen at increased partial pressures. Severe cases can result in cell damage and death, with effects most often seen in the central nervous system, lungs, and eyes. Historically, the central nervous system condition was called the Paul Bert effect, and the pulmonary condition the Lorrain Smith effect, after the researchers who pioneered the discoveries and descriptions in the late 19th century. Oxygen toxicity is a concern for underwater divers, those on high concentrations of supplemental oxygen, and those undergoing hyperbaric oxygen therapy.

<span class="mw-page-title-main">Barotrauma</span> Injury caused by external fluid pressure

Barotrauma is physical damage to body tissues caused by a difference in pressure between a gas space inside, or in contact with, the body and the surrounding gas or liquid. The initial damage is usually due to over-stretching the tissues in tension or shear, either directly by an expansion of the gas in the closed space or by pressure difference hydrostatically transmitted through the tissue. Tissue rupture may be complicated by the introduction of gas into the local tissue or circulation through the initial trauma site, which can cause blockage of circulation at distant sites or interfere with the normal function of an organ by its presence. The term is usually applied when the gas volume involved already exists prior to decompression. Barotrauma can occur during both compression and decompression events.

Decompression Illness (DCI) comprises two different conditions caused by rapid decompression of the body. These conditions present similar symptoms and require the same initial first aid. Scuba divers are trained to ascend slowly from depth to avoid DCI. Although the incidence is relatively rare, the consequences can be serious and potentially fatal, especially if untreated.

In-water recompression (IWR) or underwater oxygen treatment is the emergency treatment of decompression sickness (DCS) by returning the diver underwater to help the gas bubbles in the tissues, which are causing the symptoms, to resolve. It is a procedure that exposes the diver to significant risk which should be compared with the risk associated with the available options and balanced against the probable benefits. Some authorities recommend that it is only to be used when the time to travel to the nearest recompression chamber is too long to save the victim's life; others take a more pragmatic approach and accept that in some circumstances IWR is the best available option. The risks may not be justified for case of mild symptoms likely to resolve spontaneously, or for cases where the diver is likely to be unsafe in the water, but in-water recompression may be justified in cases where severe outcomes are likely if not recompressed, if conducted by a competent and suitably equipped team.

<span class="mw-page-title-main">Atelectasis</span> Partial collapse of a lung causing reduced gas exchange

Atelectasis is the partial collapse or closure of a lung resulting in reduced or absence in gas exchange. It is usually unilateral, affecting part or all of one lung. It is a condition where the alveoli are deflated down to little or no volume, as distinct from pulmonary consolidation, in which they are filled with liquid. It is often referred to informally as a collapsed lung, although more accurately it usually involves only a partial collapse, and that ambiguous term is also informally used for a fully collapsed lung caused by a pneumothorax.

Hyperoxia is the state of being exposed to high levels of oxygen; it may refer to organisms, cells and tissues that are experiencing excessive oxygenation, or to an abnormally high oxygen concentration in an environment.

Diving disorders, or diving related medical conditions, are conditions associated with underwater diving, and include both conditions unique to underwater diving, and those that also occur during other activities. This second group further divides conditions caused by exposure to ambient pressures significantly different from surface atmospheric pressure, and a range of conditions caused by general environment and equipment associated with diving activities.

<span class="mw-page-title-main">Respiratory disease</span> Disease of the respiratory system

Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19. Respiratory diseases can be classified in many different ways, including by the organ or tissue involved, by the type and pattern of associated signs and symptoms, or by the cause of the disease.

Freediving blackout, breath-hold blackout, or apnea blackout is a class of hypoxic blackout, a loss of consciousness caused by cerebral hypoxia towards the end of a breath-hold dive, when the swimmer does not necessarily experience an urgent need to breathe and has no other obvious medical condition that might have caused it. It can be provoked by hyperventilating just before a dive, or as a consequence of the pressure reduction on ascent, or a combination of these. Victims are often established practitioners of breath-hold diving, are fit, strong swimmers and have not experienced problems before. Blackout may also be referred to as a syncope or fainting.

<span class="mw-page-title-main">Latent hypoxia</span> Lung gas and blood oxygen concentration sufficient to support consciousness only at depth

Latent hypoxia is a condition where the oxygen content of the lungs and arterial blood is sufficient to maintain consciousness at a raised ambient pressure, but not when the pressure is reduced to normal atmospheric pressure. It usually occurs when a diver at depth has a lung gas and blood oxygen concentration that is sufficient to support consciousness at the pressure at that depth, but would be insufficient at surface pressure. This problem is associated with freediving blackout and the presence of hypoxic breathing gas mixtures in underwater breathing apparatus, particularly in diving rebreathers.

Swimming induced pulmonary edema (SIPE), also known as immersion pulmonary edema, is a life threatening condition that occurs when fluids from the blood leak abnormally from the small vessels of the lung (pulmonary capillaries) into the airspaces (alveoli).

<span class="mw-page-title-main">Decompression (diving)</span> Pressure reduction and its effects during ascent from depth

The decompression of a diver is the reduction in ambient pressure experienced during ascent from depth. It is also the process of elimination of dissolved inert gases from the diver's body which accumulate during ascent, largely during pauses in the ascent known as decompression stops, and after surfacing, until the gas concentrations reach equilibrium. Divers breathing gas at ambient pressure need to ascend at a rate determined by their exposure to pressure and the breathing gas in use. A diver who only breathes gas at atmospheric pressure when free-diving or snorkelling will not usually need to decompress. Divers using an atmospheric diving suit do not need to decompress as they are never exposed to high ambient pressure.

<span class="mw-page-title-main">Physiology of decompression</span> The physiological basis for decompression theory and practice

The physiology of decompression is the aspect of physiology which is affected by exposure to large changes in ambient pressure. It involves a complex interaction of gas solubility, partial pressures and concentration gradients, diffusion, bulk transport and bubble mechanics in living tissues. Gas is inhaled at ambient pressure, and some of this gas dissolves into the blood and other fluids. Inert gas continues to be taken up until the gas dissolved in the tissues is in a state of equilibrium with the gas in the lungs, or the ambient pressure is reduced until the inert gases dissolved in the tissues are at a higher concentration than the equilibrium state, and start diffusing out again.

Human physiology of underwater diving is the physiological influences of the underwater environment on the human diver, and adaptations to operating underwater, both during breath-hold dives and while breathing at ambient pressure from a suitable breathing gas supply. It, therefore, includes the range of physiological effects generally limited to human ambient pressure divers either freediving or using underwater breathing apparatus. Several factors influence the diver, including immersion, exposure to the water, the limitations of breath-hold endurance, variations in ambient pressure, the effects of breathing gases at raised ambient pressure, effects caused by the use of breathing apparatus, and sensory impairment. All of these may affect diver performance and safety.

Middle ear barotrauma (MEBT), also known to underwater divers as ear squeeze and reverse ear squeeze, is an injury caused by a difference in pressure between the external ear canal and the middle ear. It is common in underwater divers and usually occurs when the diver does not equalise sufficiently during descent or, less commonly, on ascent. Failure to equalise may be due to inexperience or eustachian tube dysfunction, which can have many possible causes. Unequalised ambient pressure increase during descent causes a pressure imbalance between the middle ear air space and the external auditory canal over the eardrum, referred to by divers as ear squeeze, causing inward stretching, serous effusion and haemorrhage, and eventual rupture. During ascent internal over-pressure is normally passively released through the eustachian tube, but if this does not happen the volume expansion of middle ear gas will cause outward bulging, stretching and eventual rupture of the eardrum known to divers as reverse ear squeeze. This damage causes local pain and hearing loss. Tympanic rupture during a dive can allow water into the middle ear, which can cause severe vertigo from caloric stimulation. This may cause nausea and vomiting underwater, which has a high risk of aspiration of vomit or water, with possibly fatal consequences.

References

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  2. 1 2 3 4 Rabih, Fadi; Velasquez, Alvaro (October 2019). "Splash by a beluga whale: an unusual case of salt water aspiration syndrome". Unusual Cases and Treatments in the ICU. Chest . 156 (4). Glenview, Illinois: American College of Chest Physicians: A1573. doi: 10.1016/j.chest.2019.08.1387 . ISSN   1931-3543.
  3. Jin, Faguang; Li, Congcong (June 2017). "Seawater-drowning-induced acute lung injury: From molecular mechanisms to potential treatments". Experimental and Therapeutic Medicine. 13 (6). Athens, Greece: Spandidos Publications: 2591–2598. doi:10.3892/etm.2017.4302. ISSN   1792-0981. PMC   5450642 . PMID   28587319.
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  5. 1 2 McManus, T; Ekanayake, K; Harrison, A; Whyte, K (2008-01-20). "Salt water aspiration". Eurorad. Vienna, Austria: European Society of Radiology. ISSN   1563-4086. Archived from the original on 2024-12-28. Retrieved 2024-12-28.
  6. 1 2 3 Edmonds, Carl (1970-09-01). "A salt water aspiration syndrome" . Military Medicine . 135 (9). Gaithersburg, Maryland: Association of Military Surgeons of the United States: 779–785. doi:10.1093/milmed/135.9.779. ISSN   0026-4075. PMID   4991232.
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  8. Doolette, David; Gerth, Wayne; Gault, Keith (2011-07-22). "Introduction; Discussion". Redistribution of decompression stop time from shallow to deep stops increases incidence of decompression sickness in air decompression dives (Report). Panama City Beach, Florida: United States Navy Experimental Diving Unit. pp. 1, 10–12.
  9. Bennett, Michael; Mitchell, Simon (2022). "Hyperbaric and Diving Medicine". In Loscalzo, Joseph; Fauci, Anthony; Kasper, Dennis; Hauser, Stephen; Longo, Dan; Jameson, J. Larry (eds.). Harrison's Principles of Internal Medicine . Vol. 2 (21st ed.). New York City, New York: McGraw Hill. pp. 3623–3629. ISBN   978-1-264-26851-1.
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  11. Edmonds, Carl; Walker, Douglas (1989). "Scuba diving fatalities in Australia and New Zealand: 1. The human factor". South Pacific Underwater Medicine Society Journal. 19 (3). Melbourne, Australia: South Pacific Underwater Medicine Society: 94–104. ISSN   0813-1988.