Mushroom edible

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A mushroom edible, also known as a psychedelic mushroom edible or hallucinogenic mushroom edible and sometimes as "legal shrooms", is a food item that may contain hallucinogens associated with those in psychoactive mushrooms, such as psilocybin mushrooms or Amanita muscaria mushrooms. [1] [2] [3] [4] [5] They include chocolate bars and gummies, among others. [1] [6]

Contents

Mushroom edibles have become increasingly popular in the United States in the 2020s. [3] [7] [6] They exist in a legal gray area, and may or may not be illegal depending on the ingredients. [6] [4] [2] [1] One mushroom edibles brand, Diamond Shruumz, has been linked to hundreds of poisonings, including deaths. [4] [8] The Food and Drug Administration (FDA) has warned consumers not to buy or eat mushroom edibles. [9] [10] In addition, the FDA explicitly banned Amanita muscaria ingredients in food products in the United States in late 2024. [11] [12] [13]

Description

Mushroom edibles can contain compounds found in or related to those in psilocybin mushrooms such as psilocybin, psilocin, or 4-AcO-DMT (psilacetin; "synthetic shrooms") or those in Amanita muscaria mushrooms such as muscimol or ibotenic acid. [1] [3] [4] [5] Psilocybin mushrooms are a serotonergic psychedelic, [14] [15] while Amanita muscaria mushrooms are a GABAergic hallucinogen. [16] [6] 4-AcO-DMT, a synthetic analogue of psilocybin (4-PO-DMT), is a prodrug of psilocin similarly to psilocybin itself. [3] [17] [14] Mushroom edibles may also contain completely unrelated substances and drugs, with identified compounds having included bath salts, 4-AcO-DET, the scheduled prescription drug pregabalin, and kava constituents, among others. [18] [4] [1] [19] Their ingredients are often not specified and may simply say "proprietary mushroom blend" or "magic blend". [1] [3] [20]

Mushroom edibles started being sold in the United States in the 2020s and began to surge in popularity in 2023. [3] [7] [6] They include chocolate bars, gummies, and other food items. [1] [6] The products are often sold at smokes or head shops, cannabis stores, and gas stations, as well as online. [3] [2] [7] [20] Some of the most well-known brands in the United States include PolkaDot and Tre House. [1] [7] [20] The widespread market availability of Amanita muscaria products, as opposed to hallucinogenic mushrooms in general, is a relatively recent development. [6] This mushroom is often inappropriately conflated with psilocybin mushrooms, including in terms of safety as well as possible therapeutic benefits when used medically. [6] Mushroom edibles in general exist in a legal gray area in the United States and are unregulated. [4] [2] [3] There are often knockoff or counterfeit products that imitate major brands and may have completely different ingredients in spite of similar branding. [1] [7] [20]

In December 2024, it was reported that a company called PsiloSafe had launched a testing and certification program for magic mushroom products. [21] The aim is to ensure the ingredients, potency, and safety of the products. [21] Some 15 product brands have partnered with PsiloSafe. [21]

Legality

Amanita muscaria and constituents like muscimol and ibotenic acid are not controlled substances in most of the United States and hence are considered legal. [6] [4] [2] However, other substances that may be in mushroom edibles, such as psilocybin and psilocin, are controlled substances and hence are illegal. [1] In December 2024, the U.S. Food and Drug Administration (FDA) banned the Amanita muscaria constituents muscimol, ibotenic acid, and muscarine from food products including mushroom edibles. [11] [12] [13] However, it has been said that there are uncertainties about the ability of the FDA to enforce the rule, and that the Drug Enforcement Agency (DEA) might eventually become involved. [13] The FDA and other government agencies such as the California Department of Public Health (CDPH) have warned consumers not to buy or eat mushroom edibles. [9] [10]

Poisonings

One mushroom edible brand, Diamond Shruumz, has been linked to hundreds of poisonings, including three deaths, and was recalled. [4] [8] The FDA conducted an investigation and identified ingredients including muscimol, psilacetin, psilocybin, pregabalin, and kava constituents. [18] [22] [10] It is unclear exactly why the products caused poisonings, but it may have been related to toxic amounts of muscimol or to presence of ibotenic acid, a known neurotoxin and convulsant. [18] [22] [6] In general, Amanita muscaria constituents are known to be much more toxic and less safe than psilocybin mushroom ingredients. [6] There is also little quality control in terms of the dosing of mushroom edibles, and amounts of active ingredients may vary considerably even within the same product. [1] Children have also been poisoned by mushroom edibles, for instance after stealing chocolate bars from their parents. [20]

See also

References

  1. 1 2 3 4 5 6 7 8 9 10 11 Blakinger, Keri; Sheets, Connor (9 August 2024). "Magic mushroom chocolates are having a moment. But do they even contain mushrooms?". Los Angeles Times. Retrieved 1 February 2025.
  2. 1 2 3 4 5 Ovalle, David (4 July 2024). "Psychedelic mushroom edibles promise health benefits. Be wary, experts say". Washington Post. Archived from the original on 4 July 2024. Retrieved 1 February 2025.
  3. 1 2 3 4 5 6 7 8 Syal, Akshay (18 July 2024). "Mushroom edibles are rising in popularity. It's hard to say what's in them". NBC News. Retrieved 1 February 2025.
  4. 1 2 3 4 5 6 7 8 Ducharme, Jamie (4 October 2024). "Are Mushroom Edibles Safe and Legal?". TIME. Retrieved 1 February 2025.
  5. 1 2 Rao, Devika (24 July 2024). "Mushroom edibles are tripping up users". theweek. Retrieved 1 February 2025.
  6. 1 2 3 4 5 6 7 8 9 10 11 Leas EC, Satybaldiyeva N, Kepner W, Yang KH, Harati RM, Corroon J, Rouffet M (September 2024). "Need for a Public Health Response to the Unregulated Sales of Amanita muscaria Mushrooms". Am J Prev Med. 67 (3): 458–463. doi:10.1016/j.amepre.2024.05.006. PMC   11832274 . PMID   38864780.
  7. 1 2 3 4 5 Yakowicz, Will (5 May 2024). "Your Psychedelic Gummy Is Here. (Have A Nice Trip.)". Forbes. Archived from the original on 5 May 2024. Retrieved 1 February 2025.
  8. 1 2 Johnson, Robert (11 September 2024). "A Psychedelic Debacle: 4-AcO, Microdosing, Media Panics and the Risks of Prohibition". Rolling Stone. Retrieved 1 February 2025.
  9. 1 2 Ward, James (22 November 2024). "Magic mushroom chocolate bars contain dangerous ingredients CDPH warns". The Desert Sun. Archived from the original on 1 February 2025. Retrieved 1 February 2025.
  10. 1 2 3 "Investigation of Illnesses: Diamond Shruumz-Brand Chocolate Bars, Cones, & Gummies (June 2024)". U.S. Food and Drug Administration. 1 October 2024. Retrieved 1 February 2025.
  11. 1 2 Stone, Will (21 December 2024). "The FDA restricts a psychoactive mushroom used in some edibles". NPR. Retrieved 1 February 2025.
  12. 1 2 "Edible magic mushroom: FDA is banning one specific kind in edibles". LAist. 21 December 2024. Retrieved 1 February 2025.
  13. 1 2 3 "FDA Alerts on Use of Amanita Muscaria or its Constituents in Food". U.S. Food and Drug Administration. 1 October 2024. Retrieved 1 February 2025.
  14. 1 2 Geiger HA, Wurst MG, Daniels RN (October 2018). "DARK Classics in Chemical Neuroscience: Psilocybin" (PDF). ACS Chem Neurosci. 9 (10): 2438–2447. doi:10.1021/acschemneuro.8b00186. PMID   29956917.
  15. Pepe M, Hesami M, de la Cerda KA, Perreault ML, Hsiang T, Jones AM (December 2023). "A journey with psychedelic mushrooms: From historical relevance to biology, cultivation, medicinal uses, biotechnology, and beyond". Biotechnol Adv. 69: 108247. doi:10.1016/j.biotechadv.2023.108247. PMID   37659744.
  16. Rivera-Illanes D, Recabarren-Gajardo G (September 2024). "Classics in Chemical Neuroscience: Muscimol". ACS Chem Neurosci. 15 (18): 3257–3269. doi:10.1021/acschemneuro.4c00304. PMID   39254100.
  17. Jones NT, Wagner L, Hahn MC, Scarlett CO, Wenthur CJ (2023). "In vivo validation of psilacetin as a prodrug yielding modestly lower peripheral psilocin exposure than psilocybin". Front Psychiatry. 14: 1303365. doi: 10.3389/fpsyt.2023.1303365 . PMC   10804612 . PMID   38264637.
  18. 1 2 3 Mole, Beth (5 July 2024). "What we know about microdosing candy illnesses as death investigation underway". Ars Technica. Retrieved 1 February 2025.
  19. Page, Eric S. (22 November 2024). "Seven tons of fake magic-mushroom candy bars turned over to San Diego deputies". NBC 7 San Diego. Retrieved 1 February 2025.
  20. 1 2 3 4 5 Semley, John (12 June 2023). "Cartoon packaging and an 'inconsolable' high: when magic mushroom chocolate gets into the wrong hands". the Guardian. Retrieved 2 February 2025. The brand is actually Polkadot Bar. And they've become increasingly common in the psychedelic grey market. As more states open up laws around cannabis, Polkadot Bars and a range of other magic mushroom containing-candies – including One-Up Bars, Holy Grail Bars, Magic Bars and Mushie Gummies – have become common, under-the-counter offerings in cannabis boutiques, smoke shops and corner bodegas. The bars come in a range of flavours, from Ferrero Rocher, Twix and Fruity Pebbles to matcha, blueberry acai and "strawnana".
  21. 1 2 3 Busby, Mattha (4 December 2024). "Finally, A Company Verifying Which Shroom Products Are Legit". DoubleBlind Mag. Retrieved 15 March 2025.
  22. 1 2 Stone, Will (21 August 2024). "Mushroom edibles are making people sick. Scientists still don't know why". NPR. Retrieved 1 February 2025.