Pynazolam

Not to be confused with Pyrazolam.

Pynazolam

Identifiers
IUPAC name 1-methyl-8-nitro-6-(pyridin-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
CAS Number	2034366-97-5
PubChem CID	20368157
ChemSpider	15417687
Chemical and physical data
Formula	C16H12N6O2
Molar mass	320.312 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)[N+](=O)[O-])C(=NC2)C4=CC=CC=N4
InChI InChI=1S/C16H12N6O2/c1-10-19-20-15-9-18-16(13-4-2-3-7-17-13)12-8-11(22(23)24)5-6-14(12)21(10)15/h2-8H,9H2,1H3 Key:TULLJLNDPPOHKC-UHFFFAOYSA-N

Pynazolam is a triazolobenzodiazepine derivative which has been sold online as a designer drug. It was first described in the 1970s by a team led by Leo Sternbach, ^[1] but it was never marketed.

In silico studies suggest it has relatively potent hypnotic and sedative effects. ^[2] Further research is limited, and thus very little is known about the drug's pharmacological properties.

See also

• Clonazolam
• Flunitrazolam
• Nitrazolam
• Pyeazolam
• Pyrazolam
• List of benzodiazepines

References

1. US 3970664,Sternbach LH, Walser A,"Preparation of triazolo benzodiazepines.",issued 20 July 1976, assigned to Hoffmann-LaRoche, Inc. 
2. Catalani V, Floresta G, Botha M, Corkery JM, Guirguis A, Vento A, et al. (January 2023). "In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines". Chemical Biology & Drug Design. 101 (1): 40–51. doi:10.1111/cbdd.14119. hdl: 2299/25749 . PMID   35838189.