Pynazolam

Last updated
Pynazolam
Pynazolam structure.png
Identifiers
  • 1-methyl-8-nitro-6-(pyridin-2-yl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C16H12N6O2
Molar mass 320.312 g·mol−1
3D model (JSmol)
  • CC1=NN=C2N1C3=C(C=C(C=C3)[N+](=O)[O-])C(=NC2)C4=CC=CC=N4
  • InChI=1S/C16H12N6O2/c1-10-19-20-15-9-18-16(13-4-2-3-7-17-13)12-8-11(22(23)24)5-6-14(12)21(10)15/h2-8H,9H2,1H3
  • Key:TULLJLNDPPOHKC-UHFFFAOYSA-N

Pynazolam is a triazolobenzodiazepine derivative first invented in the 1970s, [1] which has in more recent years been sold online as a designer drug. Anecdotal reports and in silico studies suggest it has relatively potent hypnotic and sedative effects.[ medical citation needed ] Anecdotal evidence has also suggested that it's subjective effects are similar to methaqualone [2] although unlike methaqualone, it cannot be smoked or vaporised due to its high melting & boiling point.

Limited pharmacological data is available [3] although there is an increasing availability of the compound for research purposes. [4]

See also

References

  1. ↑ US 3970664,Sternbach LH, Walser A,"Preparation of triazolo benzodiazepines.",issued 20 July 1976, assigned to Hoffmann-LaRoche, Inc.
  2. ↑ https://bluelight.org/xf/threads/flubromazolam-retrospective-6-years-with-the-knockout-night-nurse.892802/page-7
  3. ↑ Catalani V, Floresta G, Botha M, Corkery JM, Guirguis A, Vento A, et al. (January 2023). "In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines". Chemical Biology & Drug Design. 101 (1): 40–51. doi:10.1111/cbdd.14119. hdl: 2299/25749 . PMID   35838189.
  4. ↑ https://pubchem.ncbi.nlm.nih.gov/compound/20368157


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