2'-Oxo-PCE

Last updated
2'-Oxo-PCE
2'-Oxo-PCE.svg
Legal status
Legal status
Identifiers
  • 2-(ethylamino)-2-phenyl-cyclohexanone
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C14H19NO
Molar mass 217.312 g·mol−1
3D model (JSmol)
  • CCNC1(CCCCC1=O)C2=CC=CC=C2
  • InChI=1S/C14H19NO/c1-2-15-14(11-7-6-10-13(14)16)12-8-4-3-5-9-12/h3-5,8-9,15H,2,6-7,10-11H2,1H3
  • Key:IDLSBAANXISGEI-UHFFFAOYSA-N

2'-Oxo-PCE (also known as N-ethyldeschloroketamine, eticyclidone and O-PCE) is a dissociative anesthetic of the arylcyclohexylamine class that is closely related to deschloroketamine and eticyclidine, and has been sold online as a designer drug. [4] [5] [6] [7] [8] [9] [10] [11]

Related Research Articles

Silver Bauhinia Star Hong Kongese award

The Silver Bauhinia Star is the second Bauhinia Star rank in the honours system of Hong Kong, awarded to people who have taken a leading part in public affairs or voluntary work over a long period. The award was created in 1997 to replace the British honours system after the transfer of sovereignty to People's Republic of China and the establishment of the Hong Kong Special Administrative Region.

Bronze Bauhinia Star

The Bronze Bauhinia Star is the lowest rank in Order of the Bauhinia Star in Hong Kong, created in 1997 to replace the British honours system of the Order of the British Empire after the transfer of sovereignty to People's Republic of China and the establishment of the Hong Kong Special Administrative Region (HKSAR).

Phenformin

Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases.

<i>Journey to the West</i> (1996 TV series)

Journey to the West is a Hong Kong television series adapted from the 16th century novel of the same title. Starring Dicky Cheung, Kwong Wah, Wayne Lai and Evergreen Mak, the series was produced by TVB and was first broadcast on TVB Jade in Hong Kong in November 1996. A sequel, Journey to the West II, was broadcast in 1998, but the role of the Monkey King was played by Benny Chan instead, due to contract problems between Dicky Cheung and TVB. Cheung later reprised the role in another television series The Monkey King: Quest for the Sutra (2002), which was broadcast on TVB but not produced by the station.

Acetildenafil

Acetildenafil (hongdenafil) is a synthetic drug which acts as a phosphodiesterase inhibitor. It is an analog of sildenafil (Viagra) which has been detected in numerous different brands of supposedly "herbal" aphrodisiac products sold to boost libido and alleviate erectile dysfunction.

<i>The Legend of the Condor Heroes</i> (1994 TV series)

The Legend of the Condor Heroes is a Hong Kong television series adapted from Louis Cha's novel of the same title. The series was first broadcast on TVB Jade in 1994.

<i>The Beauty of the Game</i>

The Beauty of the Game is a 2009 TVB television drama from Hong Kong produced and created by Tsui Yu On. It is a contemporary drama focusing on recreational drug use and the negative issues surrounding Hong Kong's entertainment circle.

Arylcyclohexylamine

Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs.

<i>The Condor Heroes Return</i>

The Condor Heroes Return is a Hong Kong television series loosely based on the stories of two characters in Louis Cha's novel The Legend of the Condor Heroes. The series was released overseas in October 1993 before broadcasting on TVB Jade in Hong Kong in March 1994.

<i>State of Divinity</i> (1996 TV series)

State of Divinity is a Hong Kong television series adapted from Louis Cha's novel The Smiling, Proud Wanderer. It was first broadcast on TVB in Hong Kong in 1996.

<i>The Conquerors Story</i>

The Conqueror's Story is a Hong Kong television series based on the events in the Chu–Han Contention, an interregnum between the fall of the Qin dynasty and the founding of the Han dynasty in Chinese history. It was first broadcast in 2004 in Hong Kong on TVB Jade.

<i>The Duke of Mount Deer</i> (1998 TV series)

The Duke of Mount Deer is a Hong Kong television series adapted from Louis Cha's novel The Deer and the Cauldron. It was first aired on TVB in Hong Kong in 1998.

Methoxetamine

Methoxetamine, abbreviated as MXE, is a dissociative hallucinogen that has been sold as a designer drug. It differs from many dissociatives such as ketamine and phencyclidine (PCP) that were developed as pharmaceutical drugs for use as general anesthetics in that it was designed for grey market distribution. Due to its structural similarity to ketamine it is a controlled drug in several countries, reducing its potential as a grey market drug.

Illegal drug abuse is the action of using drugs that are prohibited by the government or strictly controlled by means of prescription to alter one’s consciousness and emotions. The Hong Kong government has a zero tolerance policy against illegal drug use. Drugs such as cannabis and ecstasy, which can be considered recreational drugs in other countries are all illegal in Hong Kong.

2-Fluorodeschloroketamine

2-Fluorodeschloroketamine is a dissociative anesthetic related to ketamine. Its sale and use as a designer drug has been reported in various countries. It is an analogue of ketamine where the chlorine group has been replaced by fluorine. Due to its recent emergence, the pharmocological specifics of the compound are mostly unclear.

<i>A New Life</i> (Hong Kong TV series)

A New Life is a 1991 Hong Kong action crime drama television series produced by TVB and starring Margie Tsang, Savio Tsang, Donnie Yen and Kitty Lai. Originally released overseas on September 23, 1991, the series is currently rerunning on TVB's Network Vision channel starting from 16 January 2016 on weekends as a part of the special, Our... Donnie Yen (我們的...甄子丹), that began running on 11 January 2016.

Substituted benzofuran

The substituted benzofurans are a class of chemical compounds based on the heterocyclyc and polycyclic compound benzofuran. Many medicines use the benzofuran core as a scaffold, but most commonly the term is used to refer to the simpler compounds in this class which include numerous psychoactive drugs, including stimulants, psychedelics and empathogens. In general, these compounds have a benzofuran core to which a 2-aminoethyl group is attached, and combined with a range of other substituents. Some psychoactive derivatives from this family have been sold under the name Benzofury.

<i>The No No Girl</i>

The No No Girl is a 2017 Hong Kong television romantic comedy drama produced by Andy Chan for TVB, starring Eddie Cheung, Adia Chan, Owen Cheung and Jeannie Chan as the main leads, with Brian Tse, Erin Wong, Helena Law, Amy Fan, Max Cheung, Eileen Yeow and Griselda Yeung as the main cast. It premiered on Hong Kong's TVB Jade and Malaysia's Astro On Demand on April 10, 2017 airing Monday through Friday during its 8:30 to 9:30 pm timeslot and concluding May 5, 2017 with a total of 20 episodes.

References

  1. "Controlled Drugs and Substances Act (S.C. 1996, c. 19) - SCHEDULE I". Government of Canada - Justice Laws Website. Retrieved 15 July 2020.
  2. Cheng WC, Dao KL (April 2020). "The Emergence of Deschloro-N-ethyl-ketamine, a Ketamine Analog, in Drug Seizures and Drug Driving Cases in Hong Kong". Journal of Analytical Toxicology. doi:10.1093/jat/bkaa038. PMID   32364605.
  3. "Fjorton nya ämnen klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 12 November 2018.
  4. "deschloro-N-ethyl-Ketamine (hydrochloride) (CAS 4551-92-2)". www.caymanchem.com.
  5. Wallach J, Brandt SD (September 2018). 1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances. Handbook of Experimental Pharmacology. 252. Springer International Publishing. pp. 305–352. doi:10.1007/164_2018_148. ISBN   978-3-030-10561-7. PMID   30196446 via Springer Link.
  6. Chong YK, Tang MH, Chan CL, Li YK, Ching CK, Mak TW (December 2017). "2-oxo-PCE: ketamine analogue on the streets". Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi. 23 (6): 665–6. doi: 10.12809/hkmj177089 . PMID   29226843.
  7. Tang MH, Chong YK, Chan CY, Ching CK, Lai CK, Li YK, Mak TW (September 2018). "Cluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE". Forensic Science International. 290: 238–243. doi:10.1016/j.forsciint.2018.07.014. PMID   30081327.
  8. Tang MH, Hung LY, Lai CK, Ching CK, Mak TW (September 2018). "9-year review of new psychoactive substance use in Hong Kong: A clinical laboratory perspective". Hong Kong Journal of Emergency Medicine. 26 (3): 179–185. doi: 10.1177/1024907918798553 . ISSN   1024-9079.
  9. Li C, Lai CK, Tang MH, Chan CC, Chong YK, Mak TW (April 2019). "Ketamine analogues multiplying in Hong Kong". Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi. 25 (2): 169. doi: 10.12809/hkmj197863 . PMID   30971512.
  10. Theofel N, Möller P, Vejmelka E, Kastner K, Roscher S, Scholtis S, Tsokos M (March 2019). "A Fatal Case Involving N-Ethyldeschloroketamine (2-Oxo-PCE) and Venlafaxine". Journal of Analytical Toxicology. 43 (2): e2–e6. doi:10.1093/jat/bky063. PMID   30365028.
  11. Tamama K, Lynch MJ (October 2019). "Newly Emerging Drugs of Abuse". Handbook of Experimental Pharmacology. 258: 463–502. doi:10.1007/164_2019_260. ISBN   978-3-030-33678-3. PMID   31595417.