OR2T27

OR2T27
Identifiers
Aliases	OR2T27 , olfactory receptor family 2 subfamily T member 27
External IDs	HomoloGene: 17468 GeneCards: OR2T27
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 248,649,838 bp [1] End 248,655,528 bp [1]
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 403239 n/a Ensembl ENSG00000187701 n/a UniProt Q8NH04 n/a RefSeq (mRNA) NM_001001824 NM_001386060 n/a RefSeq (protein) NP_001001824 n/a Location (UCSC) Chr 1: 248.65 – 248.66 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 2T27 is a protein that in humans is encoded by the OR2T27 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000187701 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR2T27 olfactory receptor, family 2, subfamily T, member 27".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2T27+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.