OR56A3

OR56A3
Identifiers
Aliases	OR56A3 , OR56A2P, OR56A3P, OR56A6, olfactory receptor family 56 subfamily A member 3
External IDs	MGI: 3030515 HomoloGene: 81538 GeneCards: OR56A3
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,938,751 bp [1] End 5,951,347 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 104,766,043 bp [2] End 104,774,730 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta testicle monocyte islet of Langerhans prefrontal cortex liver right lobe of liver anterior pituitary kidney adrenal gland Top expressed in respiratory epithelium olfactory epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390083 404318 Ensembl ENSG00000184478 ENSMUSG00000095248 UniProt Q8NH54 Q3SXH8 RefSeq (mRNA) NM_001003443 NM_207557 RefSeq (protein) NP_001003443 NP_997440 Location (UCSC) Chr 11: 5.94 – 5.95 Mb Chr 7: 104.77 – 104.77 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 56A3 is a protein that in humans is encoded by the OR56A3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000184478 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000095248 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR56A3 olfactory receptor, family 56, subfamily A, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR56A3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.