OR56B1

OR56B1
Identifiers
Aliases	OR56B1 , OR11-65, OR56B1P, olfactory receptor family 56 subfamily B member 1
External IDs	MGI: 3030338 HomoloGene: 17189 GeneCards: OR56B1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,736,448 bp [1] End 5,738,523 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 108,164,043 bp [2] End 108,165,000 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in appendix lymph node spleen tibial nerve canal of the cervix gallbladder intestinal mucosa upper lobe of left lung n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell response to stimulus signal transduction G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 387748 258163 Ensembl ENSG00000181023 ENSMUSG00000060105 UniProt Q8NGI3 Q7TRU7 RefSeq (mRNA) NM_001005180 NM_001011858 RefSeq (protein) NP_001005180 NP_001011858 Location (UCSC) Chr 11: 5.74 – 5.74 Mb Chr 7: 108.16 – 108.17 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 56B1 is a protein that in humans is encoded by the OR56B1 gene. ^[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181023 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060105 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR56B1 olfactory receptor, family 56, subfamily B, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR56B1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
• OR56B1 human gene location in the UCSC Genome Browser .
• OR56B1 human gene details in the UCSC Genome Browser .

This article incorporates text from the United States National Library of Medicine, which is in the public domain.