OR51B5

OR51B5
Identifiers
Aliases	OR51B5 , HOR5'Beta5, OR11-37, olfactory receptor family 51 subfamily B member 5
External IDs	HomoloGene: 133898 GeneCards: OR51B5
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,303,444 bp [1] End 5,505,652 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte right uterine tube Achilles tendon cervix right lobe of liver tibial nerve canal of the cervix right lobe of thyroid gland Left adrenal gland left lobe of thyroid gland n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 282763 n/a Ensembl ENSG00000167355 n/a UniProt Q9H339 n/a RefSeq (mRNA) NM_001005567 NM_001395252 n/a RefSeq (protein) NP_001005567 n/a Location (UCSC) Chr 11: 5.3 – 5.51 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 51B5 is a protein that in humans is encoded by the OR51B5 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000167355 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR51B5 olfactory receptor, family 51, subfamily B, member 5".

Further reading

• Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. Bibcode:1999PNAS...96.5129B. doi: 10.1073/pnas.96.9.5129 . PMC   21828 . PMID   10220430.
• Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi: 10.1073/pnas.97.26.14560 . PMC   18958 . PMID   11121057.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR51B5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.