OR11G2

OR11G2
Identifiers
Aliases	OR11G2 , OR14-34, olfactory receptor family 11 subfamily G member 2
External IDs	MGI: 3030578 HomoloGene: 128063 GeneCards: OR11G2
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 20,190,896 bp [1] End 20,201,075 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 C1 Start 50,852,336 bp [2] End 50,857,296 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood male reproductive system gonad testicle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390439 257884 Ensembl ENSG00000196832 ENSMUSG00000053815 UniProt Q8NGC1 Q7TRM0 RefSeq (mRNA) NM_001005503 NM_001386033 NM_001011738 RefSeq (protein) NP_001005503 NP_001011738 Location (UCSC) Chr 14: 20.19 – 20.2 Mb Chr 14: 50.85 – 50.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 11G2 is a protein that in humans is encoded by the OR11G2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196832 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000053815 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR11G2 olfactory receptor, family 11, subfamily G, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR11G2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.