OR4C13

OR4C13
Identifiers
Aliases	OR4C13 , olfactory receptor family 4 subfamily C member 13
External IDs	MGI: 3031091 HomoloGene: 115501 GeneCards: OR4C13
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p11.12 Start 49,952,391 bp [1] End 49,953,419 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E1 Start 89,708,781 bp [2] End 89,713,370 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function transmembrane signaling receptor activity G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception detection of chemical stimulus involved in sensory perception of smell sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283092 258984 Ensembl ENSG00000258817 ENSMUSG00000049057 UniProt Q8NGP0 Q8VGP0 RefSeq (mRNA) NM_001001955 NM_146982 RefSeq (protein) NP_001001955 NP_667193 Location (UCSC) Chr 11: 49.95 – 49.95 Mb Chr 2: 89.71 – 89.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4C13 is a protein that in humans is encoded by the OR4C13 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000258817 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049057 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4C13 olfactory receptor, family 4, subfamily C, member 13".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4C13+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.