OR8H1

OR8H1
Identifiers
Aliases	OR8H1 , OR11-180, olfactory receptor family 8 subfamily H member 1
External IDs	MGI: 3030933 HomoloGene: 107003 GeneCards: OR8H1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,288,462 bp [1] End 56,292,254 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,785,470 bp [2] End 86,791,037 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in aorta ascending aorta n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity odorant binding Cellular component integral component of membrane plasma membrane membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219469 258764 Ensembl ENSG00000262611 ENSG00000181693 ENSMUSG00000075168 UniProt Q8NGG4 Q8VG37 RefSeq (mRNA) NM_001005199 NM_146768 RefSeq (protein) NP_001005199 NP_666979 Location (UCSC) Chr 11: 56.29 – 56.29 Mb Chr 2: 86.79 – 86.79 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8H1 is a protein that in humans is encoded by the OR8H1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000181693 GRCh38: Ensembl release 89: ENSG00000262611, ENSG00000181693 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075168 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8H1 olfactory receptor, family 8, subfamily H, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8H1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.