OR13J1

OR13J1
Identifiers
Aliases	OR13J1 , OR9-2, olfactory receptor family 13 subfamily J member 1
External IDs	MGI: 1860080 HomoloGene: 10460 GeneCards: OR13J1
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9p13.3 Start 35,869,463 bp [1] End 35,870,401 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 A5 Start 43,704,562 bp [2] End 43,710,255 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex hippocampus proper superior frontal gyrus putamen dorsolateral prefrontal cortex temporal lobe amygdala Brodmann area 9 caudate nucleus nucleus accumbens Top expressed in intestinal villus entorhinal cortex extraocular muscle medial ganglionic eminence tracheobronchial tree medulla oblongata primary motor cortex soleus muscle inferior colliculus tibialis anterior muscle More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 392309 56015 Ensembl ENSG00000168828 ENSMUSG00000046450 UniProt Q8NGT2 Q9QZ18 RefSeq (mRNA) NM_001004487 NM_019486 RefSeq (protein) NP_001004487 NP_062359 Location (UCSC) Chr 9: 35.87 – 35.87 Mb Chr 4: 43.7 – 43.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 13J1 is a protein that in humans is encoded by the OR13J1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000168828 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000046450 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR13J1 olfactory receptor, family 13, subfamily J, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.145.6233 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.

External links

• OR13J1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.