OR11H1

OR11H1
Identifiers
Aliases	OR11H1 , OR22-1, OR11H12, olfactory receptor family 11 subfamily H member 1
External IDs	HomoloGene: 84609 GeneCards: OR11H1
Gene location (Human) Chr. Chromosome 22 (human) [1] Band 22q11.1 Start 15,528,192 bp [1] End 15,529,139 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in circulatory system aorta thoracic aorta ascending aorta n/a More reference expression data BioGPS n/a
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81061 n/a Ensembl ENSG00000130538 n/a UniProt Q8NG94 n/a RefSeq (mRNA) NM_001005239 n/a RefSeq (protein) NP_001005239 n/a Location (UCSC) Chr 22: 15.53 – 15.53 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 11H1 is a protein that in humans is encoded by the OR11H1 gene. ^{[3] [4]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000130538 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (Sep 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
4. "Entrez Gene: OR11H1 olfactory receptor, family 11, subfamily H, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR11H1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.