OR4N4

OR4N4
Identifiers
Aliases	OR4N4 , OR15-1, OR15-5, olfactory receptor family 4 subfamily N member 4
External IDs	MGI: 3030566 HomoloGene: 72012 GeneCards: OR4N4
Gene location (Human) Chr. Chromosome 15 (human) [1] Band 15q11.2 Start 22,094,522 bp [1] End 22,095,472 bp [1]
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • membrane • plasma membrane • integral component of membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	283694	258659
Ensembl	ENSG00000183706 ENSG00000288501	ENSMUSG00000091873
UniProt	Q8N0Y3	Q8VFT5
RefSeq (mRNA)	NM_001005241	NM_146665
RefSeq (protein)	NP_001005241	NP_666876
Location (UCSC)	Chr 15: 22.09 – 22.1 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4N4 is a protein that in humans is encoded by the OR4N4 gene. ^[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. ENSG00000288501 GRCh38: Ensembl release 89: ENSG00000183706, ENSG00000288501 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4N4 olfactory receptor, family 4, subfamily N, member 4".

Further reading

• Ota T, Suzuki Y, Nishikawa T (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID   14702039.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR4N4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.