OR10K1

OR10K1
Identifiers
Aliases	OR10K1 , OR1-6, olfactory receptor family 10 subfamily K member 1
External IDs	HomoloGene: 84605 GeneCards: OR10K1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 158,461,574 bp [1] End 158,470,857 bp [1]
RNA expression pattern Bgee Top expressed in lung multicellular organism More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	391109	n/a
Ensembl	ENSG00000173285	n/a
UniProt	Q8NGX5	n/a
RefSeq (mRNA)	NM_001004473	n/a
RefSeq (protein)	NP_001004473	n/a
Location (UCSC)	Chr 1: 158.46 – 158.47 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptor 10K1 is a protein that in humans is encoded by the OR10K1 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

Amino acid sequence

MEQVNKTVVR EFVVLGFSSL ARLQQLLFVI FLLLYLFTLG TNAIIISTIV LDRALHTPMY FFLAILSCSE ICYTFVIVPK MLVDLLSQKK TISFLGCAIQ MFSFLFFGSS HSFLLAAMGY DRYMAICNPL RYSVLMGHGV CMGLMAAACA CGFTVSLVTT SLVFHLPFHS SNQLHHFFCD ISPVLKLASQ HSGFSQLVIF MLGVFALVIP LLLILVSYIR IISAILKIPS SVGRYKTFST CASHLIVVTV HYSCASFIYL RPKTNYTSSQ DTLISVSYTI LTPLFNPMIY SLRNKEFKSA LRRTIGQTFY PLS ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000173285 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR10K1 olfactory receptor, family 10, subfamily K, member 1".
4. "ORDB: Chemosensory Receptors - ORL3001".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10K1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.