OR10G2

OR10G2
Identifiers
Aliases	OR10G2 , OR14-41, olfactory receptor family 10 subfamily G member 2
External IDs	MGI: 3031345 HomoloGene: 87788 GeneCards: OR10G2
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 21,633,836 bp [1] End 21,634,940 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 C2 Start 52,627,251 bp [2] End 52,634,836 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lymph node appendix spleen Top expressed in hypothalamus neural tube olfactory bulb blastocyst More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 26534 258268 Ensembl ENSG00000255582 ENSMUSG00000063867 UniProt n a E9PWU0 RefSeq (mRNA) NM_001005466 NM_146271 RefSeq (protein) n/a NP_666383 Location (UCSC) Chr 14: 21.63 – 21.63 Mb Chr 14: 52.63 – 52.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10G2 is a protein that in humans is encoded by the OR10G2 gene. ^{[5] [6]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes.^{[ citation needed ]} Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[6]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000255582 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000063867 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koop BF, Rowen L, Wang K, Kuo CL, Seto D, Lenstra JA, Howard S, Shan W, Deshpande P, Hood L (Jun 1994). "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA". Genomics. 19 (3): 478–93. doi:10.1006/geno.1994.1097. PMID   8188290.
6. "Entrez Gene: OR10G2 olfactory receptor, family 10, subfamily G, member 2".

Further reading

• Boysen C, Simon MI, Hood L (1997). "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4): 330–8. doi: 10.1101/gr.7.4.330 . PMID   9110172.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10G2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.