OR5M3

OR5M3
Identifiers
Aliases	OR5M3 , OR11-191, olfactory receptor family 5 subfamily M member 3
External IDs	MGI: 3030866 HomoloGene: 17299 GeneCards: OR5M3
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,469,274 bp [1] End 56,473,352 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 85,835,884 bp [2] End 85,839,469 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ascending aorta thoracic aorta multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219482 258572 Ensembl ENSG00000174937 ENSMUSG00000042796 UniProt Q8NGP4 A2ATE5 RefSeq (mRNA) NM_001004742 NM_146579 RefSeq (protein) NP_001004742 NP_666790 Location (UCSC) Chr 11: 56.47 – 56.47 Mb Chr 2: 85.84 – 85.84 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 5M3 is a protein that in humans is encoded by the OR5M3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000174937 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042796 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5M3 olfactory receptor, family 5, subfamily M, member 3".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5M3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.