OR8K5

OR8K5
Identifiers
Aliases	OR8K5 , OR11-174, olfactory receptor family 8 subfamily K member 5
External IDs	MGI: 3030887 HomoloGene: 74197 GeneCards: OR8K5
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,159,394 bp [1] End 56,160,317 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,144,687 bp [2] End 86,145,628 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219453 257974 Ensembl ENSG00000181752 ENSMUSG00000075192 UniProt Q8NH50 L7MU59 RefSeq (mRNA) NM_001004058 NM_001177857 RefSeq (protein) NP_001004058 NP_001171328 Location (UCSC) Chr 11: 56.16 – 56.16 Mb Chr 2: 86.14 – 86.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8K5 is a protein that in humans is encoded by the OR8K5 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181752 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075192 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8K5 olfactory receptor, family 8, subfamily K, member 5".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8K5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.