OR10V1

OR10V1
Identifiers
Aliases	OR10V1 , OR11-256, olfactory receptor family 10 subfamily V member 1
External IDs	MGI: 3031254 HomoloGene: 17234 GeneCards: OR10V1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 59,712,916 bp [1] End 59,713,845 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 11,863,929 bp [2] End 11,875,443 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in urinary bladder Top expressed in respiratory epithelium olfactory epithelium morula urinary bladder ovary mirror adrenal gland hypothalamus white adipose tissue islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390201 258405 Ensembl ENSG00000172289 ENSMUSG00000060878 UniProt Q8NGI7 Q8VF55 RefSeq (mRNA) NM_001005324 NM_146410 RefSeq (protein) NP_001005324 NP_666522 Location (UCSC) Chr 11: 59.71 – 59.71 Mb Chr 19: 11.86 – 11.88 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 10V1 is a protein that in humans is encoded by the OR10V1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172289 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060878 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10V1 olfactory receptor, family 10, subfamily V, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10V1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.