OR4C11

OR4C11
Identifiers
Aliases	OR4C11 , OR11-136, OR4C11P, olfactory receptor family 4 subfamily C member 11
External IDs	MGI: 3031035 HomoloGene: 81567 GeneCards: OR4C11
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q11 Start 55,602,360 bp [1] End 55,607,645 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 E1 Start 88,623,380 bp [2] End 88,627,171 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ascending aorta thoracic aorta multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219429 258897 Ensembl ENSG00000172188 ENSMUSG00000059023 UniProt Q6IEV9 Q8VGF5 RefSeq (mRNA) NM_001004700 NM_146895 RefSeq (protein) NP_001004700 NP_667106 Location (UCSC) Chr 11: 55.6 – 55.61 Mb Chr 2: 88.62 – 88.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4C11 is a protein that in humans is encoded by the OR4C11 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172188 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059023 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4C11 olfactory receptor, family 4, subfamily C, member 11".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4C11+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.