OR1N1

OR1N1
Identifiers
Aliases	OR1N1 , OR1-26, OR1N3, OR9-22, olfactory receptor family 1 subfamily N member 1
External IDs	MGI: 3030185 HomoloGene: 10583 GeneCards: OR1N1
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,526,358 bp [1] End 122,527,296 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 36,747,551 bp [2] End 36,752,672 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence endometrium liver urinary system renal cortex myometrium temporal lobe amygdala n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 138883 258944 Ensembl ENSG00000171505 ENSMUSG00000075383 UniProt Q8NGS0 Q8VGK1 RefSeq (mRNA) NM_012363 NM_146942 RefSeq (protein) NP_036495 NP_667153 Location (UCSC) Chr 9: 122.53 – 122.53 Mb Chr 2: 36.75 – 36.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 1N1 is a protein that in humans is encoded by the OR1N1 gene. ^{[5] [6]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[6]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171505 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075383 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID   9500546. S2CID   31129045.
6. "Entrez Gene: OR1N1 olfactory receptor, family 1, subfamily N, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR1N1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.