OR13C3

OR13C3
Identifiers
Aliases	OR13C3 , OR37G, OR9-8, olfactory receptor family 13 subfamily C member 3
External IDs	MGI: 3030107 HomoloGene: 73999 GeneCards: OR13C3
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q31.1 Start 104,535,749 bp [1] End 104,536,856 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 B2 Start 52,852,154 bp [2] End 52,859,236 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle multicellular organism Top expressed in respiratory epithelium spermatid peripheral nervous system olfactory epithelium testicle More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 138803 258821 Ensembl ENSG00000204246 ENSMUSG00000049648 UniProt Q8NGS6 Q8VG87 RefSeq (mRNA) NM_001001961 NM_146824 RefSeq (protein) NP_001001961 NP_667035 Location (UCSC) Chr 9: 104.54 – 104.54 Mb Chr 4: 52.85 – 52.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 13C3 is a protein that in humans is encoded by the OR13C3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000204246 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049648 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR13C3 olfactory receptor, family 13, subfamily C, member 3".

Further reading

• Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human". Genomics. 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID   12906860.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.

External links

• OR13C3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.