OR1I1

OR1I1
Identifiers
Aliases	OR1I1 , OR19-20, OR1I1P, OR1I1Q, olfactory receptor family 1 subfamily I member 1
External IDs	MGI: 3031191; HomoloGene: 72920; GeneCards: OR1I1; OMA:OR1I1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.12 Start 15,082,211 bp [1] End 15,092,970 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 C1 Start 78,446,837 bp [2] End 78,453,908 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibialis anterior muscle gonad mucosa of ileum testicle deltoid muscle skin of hip skin of thigh placenta blood gastric mucosa Top expressed in respiratory epithelium nasal epithelium olfactory epithelium olfactory bulb More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity transmembrane signaling receptor activity olfactory receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 126370 257883 Ensembl ENSG00000094661 ENSMUSG00000071185 UniProt O60431 Q7TQU7 RefSeq (mRNA) NM_001004713 NM_001011737 RefSeq (protein) NP_001004713 NP_001011737 Location (UCSC) Chr 19: 15.08 – 15.09 Mb Chr 10: 78.45 – 78.45 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 1I1 is a protein that in humans is encoded by the OR1I1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000094661 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000071185 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1I1 olfactory receptor, family 1, subfamily I, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi: 10.1038/nature02399 . PMID   15057824.

External links

• OR1I1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.