OR10C1

OR10C1
Identifiers
Aliases	OR10C1 , OR10C1P, OR10C2, OR6-31, hs6M1-17, olfactory receptor family 10 subfamily C member 1 (gene/pseudogene), olfactory receptor family 10 subfamily C member 1
External IDs	MGI: 2177478 HomoloGene: 71990 GeneCards: OR10C1
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p22.1 Start 29,439,306 bp [1] End 29,440,977 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 37,518,841 bp [2] End 37,524,009 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cells n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 442194 258506 Ensembl ENSG00000206474 ENSMUSG00000049561 UniProt Q96KK4 Q8VFE2 RefSeq (mRNA) NM_013941 NM_146513 RefSeq (protein) NP_039229 NP_666724 Location (UCSC) Chr 6: 29.44 – 29.44 Mb Chr 17: 37.52 – 37.52 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10C1 is a protein that in humans is encoded by the OR10C1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000206474 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049561 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10C1 olfactory receptor, family 10, subfamily C, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Volz A, Ehlers A, Younger R, et al. (2003). "Complex transcription and splicing of odorant receptor genes". J. Biol. Chem. 278 (22): 19691–701. doi: 10.1074/jbc.M212424200 . PMID   12637542.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10C1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.